+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn

+ Translate
+ Recently Requested

Treatment of IV catheter-associated infections Guidelines for 2001 based on anecdotes, wisdom or facts

Treatment of IV catheter-associated infections Guidelines for 2001 based on anecdotes, wisdom or facts

Abstracts of the Interscience Conference on Antimicrobial Agents & Chemotherapy 41: 503

Guidelines for management of intravascular catheter-related infections were recently published. There were scant data and few prospective studies to guide the authors. Recommendations with good supportive evidence: For coag-neg. staph CRBSI - tx empirically w/vancomycin, change to semi-synthetic PCN if susceptible; for treatment failure (persistent fever/positive blood cultures, or relapse after antibiotics d/c'd) remove catheter. For S. aureus CRBSI - remove catheter; use beta-lactam antibiotics when isolate susceptible; w/PCN allergy w/o anaphylaxis/angioedema, 1st generation cephalosporins can be used; w/serious beta-lactam allergy or MRSA, use vancomycin. For GNR CRBSI - w/non-aeruginosa pseudomonads, B. cepacia, Stenotrophomonas, Agrobacterium, and Acinetobacter, seriously consider catheter removal. For misc. CRBSI - w/Bacillus or Corynebacteria, remove catheter; w/mycobacteria (eg M. fortuitum) remove the catheter. For Candida CRBSI - remove catheter; use systemic therapy for all patients; ampho-B recommended for suspected catheter-related candidemia if hemodynamically unstable or if has received prolonged fluconazole; use fluconazole if hemodynamically stable and no recent fluconazole use, or if fluconazole susceptible isolate; tx for 14 d. after last positive blood culture and symptoms of infection resolved; use ampho-B for C. krusei; remove tunneled/implanted catheters w/documented catheter-related fungemia. For septic thrombosis - remove catheter; surgical excision/repair is needed w/peripheral arterial pseudoaneurysms; anticoagulate for great central vein septic thrombosis; when due to Candida, use prolonged ampho-B or fluconazole if susceptible. For persistent bloodstream infection and endocarditis - remove involved catheter; for empiric therapy include staphylococcal coverage; with rare exception, Candida endocarditis requires surgery.

(PDF emailed within 1 workday: $29.90)

Accession: 035980506

Download citation: RISBibTeXText

Related references

Anecdotes as evidence: We need guidelines for reporting anecdotes of suspected adverse drug reactions. BMJ 326(7403): 1346, 2003

Facts, anecdotes, and new horizons in the medical treatment of duodenal ulcers. Surgical Clinics of North America 56(6): 1243-1248, 1976

Intravascular catheter-related infections Guidelines for prevention and treatment. Abstracts of the Interscience Conference on Antimicrobial Agents & Chemotherapy 40: 531, 2000

Nurses' knowledge of evidence-based guidelines on the prevention of peripheral venous catheter-related infections: a multicentre survey. Journal of Clinical Nursing 23(17-18): 2578-2588, 2015

Prevention of central venous catheter-associated bloodstream infections: A questionnaire evaluating the knowledge of the selected 11 evidence-based guidelines by Polish nurses. American Journal of Infection Control 43(12): 1368-1371, 2016

Guidelines for the prevention of intravascular catheter-related infections: recommendations relevant to interventional radiology for venous catheter placement and maintenance. Journal of Vascular and Interventional Radiology 23(8): 997-1007, 2013

Guidelines for the treatment of short-term intravascular catheter-related infections in adults; SEIMC-SEMICYUC Consensus Conference. Enfermedades Infecciosas Y Microbiologia Clinica 22(2): 92-101, 2004

Implementing clinical guidelines to prevent catheter-associated urinary tract infections and improve catheter care in nursing homes: Systematic review. American Journal of Infection Control 45(5): 471-476, 2018

Consensus guidelines for the prevention and treatment of catheter-related infections and peritonitis in pediatric patients receiving peritoneal dialysis: 2012 update. Peritoneal Dialysis International 32 Suppl 2: S32-S86, 2013

Implications of 2001 cholesterol treatment guidelines based on a retrospective analysis of a high-risk patient cohort. American Journal of Cardiology 89(6): 765-766, 2002

Prophylactic antibiotic treatment following laparoscopic robot-assisted radical prostatectomy for the prevention of catheter-associated urinary tract infections: did the AUA guidelines make a difference?. Journal of Robotic Surgery, 2016

S2k guidelines for skin and soft tissue infections Excerpts from the S2k guidelines for "calculated initial parenteral treatment of bacterial infections in adults - update 2018". Journal der Deutschen Dermatologischen Gesellschaft 17(3): 345-369, 2019

Diffusion of new technology for the treatment of renovascular hypertension in the United States: surgical revascularization versus catheter-based therapy, 1988-2001. Journal of Vascular Surgery 40(4): 717-723, 2004

Comparison of treatment principles of elderly hypertensive patients with different cardiovascular risks based on Hungarian and international guidelines (2001-2015). Orvosi Hetilap 157(7): 247-259, 2016

Antiplatelet Treatment for Catheter-Based Interventions in High-Risk Patients: Current Guidelines and Expert Opinion. Hamostaseologie 38(4): 229-235, 2018