+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Treatment of acute wheezing episodes in young children

Treatment of acute wheezing episodes in young children

Journal of Pediatrics 145(2): 151-152

The problem of the interference of celiac disease (CD) with the male reproductive system is made evident both by the recognized adverse effects on female reproduction and by the multifactorial nature of the disease. It is important to consider CD as a multifactorial condition since its diverse effects can be modulated, besides gluten, by different concurrent genetic and environmental factors. The male CD patient has a greater risk of infertility and other reproductive disturbances, as well as a greater incidence of hypoandrogenism. In this paper the problems of CD associated to endocrine disorders and to deficiencies of micronutrients are discussed. Affected males show a picture of tissue resistance to androgens. Moreover, attention should be paid to increases of FSH and prolactin; these are not associated to infertility and/or impotence, but they may indicate an imbalance at hypothalamus-pituitary level, with general effects on health: an example is the increased risk of male osteoporosis in CD patients. Hormone alterations are reversible upon start of the gluten-free diet, emphasizing the importance of early diagnosis; this should be performed in the case of clinical suspicion, e.g., unexplained hypoandrogenism. As regards nutritional aspects, the folic acid deficiency of CD can affect rapidly proliferating tissues, such as the embryo and the seminiferous epithelium. More attention should be paid to deficiencies of fat-soluble vitamins, such as A and E, observed in CD. Vitamin A is important for Sertoli cell function as well as for early spermatogenetic phases. Vitamin E supports the correct differentiation and function of epidydimal epithelium, spermatid maturation and secretion of proteins by the prostate. Therefore, CD male patients should be considered as vulnerable subjects; thus, the detection of early biomarkers of andrological or endocrinological dysfunctions should trigger timely strategies for prevention and treatment.

(PDF same-day service: $19.90)

Accession: 035980824

Download citation: RISBibTeXText

PMID: 15289758

DOI: 10.1016/j.jpeds.2004.05.029

Related references

Macrolides for Acute Wheezing Episodes in Preschool Children. Pediatric Allergy, Immunology, and Pulmonology 29(2): 100-103, 2016

The association between influenza virus and acute episodes of wheezing in asthmatic children. Pediatric Research 47(4 Part 2): 156A, April, 2000

Cockroach and dust mite allergen exposure in homes of children with acute episodes of wheezing. Journal of Allergy & Clinical Immunology 105(1 part 2): S80-S81, 2000

Effect of high starting dose of budesonide inhalation suspension on serum cortisol concentration in young children with recurrent wheezing episodes. Journal of Asthma 40(6): 625-629, 2003

Treatment of recurrent acute wheezing episodes in infancy with oral salbutamol and prednisolone. European Journal of Pediatrics 155(6): 512-516, 1996

Exhaled Nitric Oxide in Acute Phase of Bronchiolitis and Its Relation with Episodes of Subsequent Wheezing in Children of Preschool Age. Pediatric Allergy, Immunology, and Pulmonology 25(2): 92-96, 2012

An update on the efficacy of oral corticosteroids in the treatment of wheezing episodes in preschool children. Therapeutic Advances in Respiratory Disease 8(6): 182-190, 2015

Rapid induction of clinical response with a short-term high-dose starting schedule of budesonide nebulizing suspension in young children with recurrent wheezing episodes. Journal of Allergy and Clinical Immunology 101(4 Pt 1): 464-469, 1998

Efficacy of oral corticosteroids in the treatment of acute wheezing episodes in asthmatic preschoolers: Systematic review with meta-analysis. Pediatric Pulmonology 51(8): 868-876, 2016

Human rhinovirus infection in young African children with acute wheezing. Bmc Infectious Diseases 11(): 65-65, 2011

One-year follow-up of young children hospitalized for wheezing: the influence of early anti-inflammatory therapy and risk factors for subsequent wheezing and asthma. Pediatric Pulmonology 26(2): 113-119, 1998

Differential diagnosis and treatment of wheezing and asthma in young children. Clinical Pediatrics 47(8): 735-743, 2008

Is Montelukast effective in the treatment of young children wheezing with a viral illness?. Pediatric Research 53(4 Part 2): 21A-22A, April, 2003

Chest X-ray essential in children with initial wheezing episodes. American Journal of Emergency Medicine 13(5): 607-608, 1995

Acute splenic sequestration crises (ASSC) in young children with sickle cell anemia. Clinical observations in 20 episodes in 14 children. Clinical Pediatrics 11(12): 701-704, 1972