EurekaMag.com logo
+ Site Statistics
References:
53,623,987
Abstracts:
29,492,080
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Trends in antimicrobial resistance rates of Staphylococcus aureus causing bloodstream infection and nosocomial pneumonia A report from the Euro-SENTRY program 2000-2002



Trends in antimicrobial resistance rates of Staphylococcus aureus causing bloodstream infection and nosocomial pneumonia A report from the Euro-SENTRY program 2000-2002



Abstracts Of The Interscience Conference On Antimicrobial Agents & Chemotherapy. 43: 144



Background: We analyzed the SENTRY Europe data from the years 2000-2002 to update the antimicrobial resistance rates in S. aureus isolates from bloodstream (BSI) and lower respiratory tract infections (LRTI) from a network of European hospitals. Methods: A total of 4,416 S. aureus strains referred from 18-31 hospitals in 13-18 countries were included. Antimicrobial susceptibility to 28 antimicrobial agents was tested by refence broth microdilution method (NCCLS). Results: 3,177 isolates (72%) were recovered from BSI and 1,279 (28%) from LRTI; 46.2% corresponded to nosocomial infections and 29.3% were from patients (pts) admitted to intensive care units (ICU). S. aureus was the second most frequent reported species in BSI and LRTI. The mean (inter-centre range) proportion of non-susceptible (NS) oxacillin isolates (MRSA) were: 42% (0-84) in ICU pts vs 27% in non-ICU pts (p<0.001); NS quinupristin-dalfopristin in ICU vs non-ICU patients: 2.3 vs 0.7% (p<0.001), ciprofloxacin: 43 vs 29.5% (p<0.001); teicoplanin: 0.2% vs 0.1%; rifampin: 14 vs 6% (p<0.001); The mean proportion of gentamicin-resistant isolates was 27% in ICU pts vs 14% in non-ICU. All isolates were susceptible to linezolid and vancomycin. Significant trend toward decreasing resistance was observed for oxacillin, gentamicin, rifampin, and ciprofloxacin in ICU patients (p<0.01), whereas ciprofloxacin and oxacillin showed an increasing resistance trend in non-ICU patients (p<0.01 and p<0.05, respectively). Conclusions: These data confirm the decreasing resistance of MRSA to gentamicin and rifampin in Europe. Large intercountry and intercentre variation of MRSA prevalence was also confirmed. MRSA was more frequent in ICU admitted patients No strains with decreased susceptibility to vancomycin or linezolid were detected in the last years.

(PDF 0-2 workdays service: $29.90)

Accession: 035985210

Download citation: RISBibTeXText



Related references

Salmonella spp. isolates causing bloodstream infections in Latin America: Report of antimicrobial activity from the SENTRY Antimicrobial Surveillance Program (1997-2000). Diagnostic Microbiology and Infectious Disease 44(3): 313-318, 2002

Occurrence and antimicrobial resistance pattern comparisons among bloodstream infection isolates from the SENTRY Antimicrobial Surveillance Program (1997-2002). Diagnostic Microbiology and Infectious Disease 50(1): 59-69, 2004

Variation in Candida spp. distribution and antifungal resistance rates among bloodstream infection isolates by patient age: report from the SENTRY Antimicrobial Surveillance Program (2008-2009). Diagnostic Microbiology and Infectious Disease 68(3): 278-283, 2011

Geographic variations in species distribution and echinocandin and azole antifungal resistance rates among Candida bloodstream infection isolates: report from the SENTRY Antimicrobial Surveillance Program (2008 to 2009). Journal of Clinical Microbiology 49(1): 396-399, 2011

Age-related trends in pathogen frequency and antimicrobial susceptibility of bloodstream isolates in North America SENTRY Antimicrobial Surveillance Program, 1997-2000. International Journal of Antimicrobial Agents 20(6): 412-418, December, 2002

Urinary tract infection trends in Latin American hospitals: Report from the SENTRY Antimicrobial Surveillance Program (1997-2000). Diagnostic Microbiology and Infectious Disease 44(3): 289-299, 2002

Comparative activity of linezolid against respiratory tract infection isolates of Staphylococcus aureus: an 11-year report from the SENTRY Antimicrobial Surveillance Program. International Journal of Antimicrobial Agents 37(6): 584-585, 2011

Penicillin and macrolides resistance trends among Streptococcus pneumoniae isolated in Latin America between 1998 and 2002 Report of SENTRY antimicrobial surveillance program. Abstracts of the Interscience Conference on Antimicrobial Agents & Chemotherapy 43: 132, 2003

Trends in antimicrobial susceptibility of bacterial pathogens isolated from patients with bloodstream infections in North America SENTRY Program, 1997-2000. Abstracts of the Interscience Conference on Antimicrobial Agents & Chemotherapy 41: 116, 2001

Trends in antifungal susceptibility of Candida spp. isolated from pediatric and adult patients with bloodstream infections: SENTRY Antimicrobial Surveillance Program, 1997 to 2000. Journal of Clinical Microbiology 40(3): 852-856, 2002

Pathogen occurrence and antimicrobial resistance trends among urinary tract infection isolates in the Asia-Western Pacific region: Report from the SENTRY antimicrobial surveillance program, 1998-1999. International Journal of Antimicrobial Agents 20(1): 10-17, July, 2002

Changing patterns of bacterial pathogens and their antimicrobial susceptibility profiles in patients hospitalized with pneumonia Report from the SENTRY Antimicrobial Surveillance Program, 2002. Abstracts of the Interscience Conference on Antimicrobial Agents & Chemotherapy 43: 124, 2003

Candida bloodstream infections: comparison of species distributions and antifungal resistance patterns in community-onset and nosocomial isolates in the SENTRY Antimicrobial Surveillance Program, 2008-2009. Antimicrobial Agents and ChemoTherapy 55(2): 561-566, 2011

Oxacillin- and multiple drug-resistance among Staphylococcus aureus Results of the SENTRY antimicrobial resistance surveillance program, 1997-1999. Abstracts of the Interscience Conference on Antimicrobial Agents & Chemotherapy 40: 68, 2000

Antimicrobial resistance among community-acquired pneumonia isolates in Europe: first results from the SENTRY antimicrobial surveillance program 1997. SENTRY Participants Group. International Journal of Infectious Diseases 3(3): 153-156, 1999