EurekaMag.com logo
+ Site Statistics
References:
53,623,987
Abstracts:
29,492,080
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Trends in the occurrence and clinical features of Crohns disease and ulcerative colitis in a university hospital in southeastern Brazil



Trends in the occurrence and clinical features of Crohns disease and ulcerative colitis in a university hospital in southeastern Brazil



Arquivos de Gastroenterologia 39(2): 98-105



Background - Crohn's disease and ulcerative colitis are regarded as uncommon in developing countries, but studies on their occurrence in Brazil are scarce. Aims - To determine the occurrence of Crohn's disease and ulcerative colitis in a Brazilian university hospital throughout a 20-year period, and analyze the demographical, clinical and evolutive features of these cases. Methods - The frequencies of new cases of Crohn's disease and ulcerative colitis admitted from January 1980 up to December 1999 were calculated and a descriptive analysis of the features of all cases seen from January 1990 up to December 1999 was performed. Results - A total of 257 new cases (126 with Crohn's disease and 131 with ulcerative colitis) was recorded. The frequencies of admissions for both Crohn's disease and ulcerative colitis have increased progressively from 40 up to 61 cases/10.000 new admissions and Crohn's disease gradually became more common than ulcerative colitis. For both diseases, there was predominance of women, age at admission in the range of 30-40 years, Caucasian origin, married state and non-smokers. Digestive symptoms presented were similar to those already described for both diseases and there were no differences between Crohn's disease and ulcerative colitis regarding the frequencies of general complaints and extra-intestinal manifestations (29.5% vs 23.3%), including thromboembolism (5.9% vs 5.4%). Obstruction and/or perforation were seen in up to 59.2% of Crohn's disease cases, whereas 53.7% of all ulcerative colitis cases presented as severe forms. In Crohn's disease cases with obstruction, smoking was significantly more common than in non-complicated cases. In ulcerative colitis cases of increased severity, general complaints, extra-intestinal manifestations and pancolitis were significantly more frequent than in less severe forms. Conclusions - For the last 20 years, there have been an increased frequency of admission of inflammatory bowel diseases, and Crohn's disease have become more prevalent than ulcerative colitis. Demographical, clinical and evolutive features of these diseases seems to be similar to those already described, but there seems to be a predominance of more severe forms of both diseases.

(PDF 0-2 workdays service: $29.90)

Accession: 035985612

Download citation: RISBibTeXText



Related references

Trends in the occurrence (1980-1999) and clinical features of Crohn's disease and ulcerative colitis in a university hospital in southeastern Brazil. Arquivos de Gastroenterologia 39(2): 98-105, 2003

Crohns disease and ulcerative colitis Divergent trends in hospital admission rates. Gut 50(Supplement 2): A75, April, 2002

Methods of diagnosing a clinical subtype of Crohns disease with features of ulcerative colitis. Official Gazette of the United States Patent & Trademark Office Patents 1219(4): 3308, Feb 23, 1999

Method of diagnosing a clinical subtype of crohns disease with features of ulcerative colitis. Official Gazette of the United States Patent & Trademark Office Patents 1223(5), Jun 29, 1999

Reports of new cases of ulcerative colitis and crohns disease in norway in 1972 clinical features. Scandinavian Journal of Gastroenterology Supplement 8(20): 37-38, 1973

Mortality Trends in Crohns Disease and Ulcerative Colitis. Inflammatory Bowel Diseases 22(2): 416-423, 2016

Crohns disease and ulcerative colitis relative incidence and comparative features. Australian & New Zealand Journal of Medicine 11(2): 226, 1981

Crohns disease of the colon part 4 clinical features of crohns ileo colitis. American Journal of Gastroenterology 64(3): 191-199, 1975

Familial occurrence of ibd in ulcerative colitis and crohns disease patients and the significance of this for disease behaviour. Digestive Disease Week Abstracts & Itinerary Planner : Abstract No S1400, 2003

Features of colon mucosa inflammation in nonspecific ulcerative colitis and crohns disease. Arkhiv Patologii 44(9): 32-39, 1982

Lack of seasonality in hospital admissions for crohns disease and ulcerative colitis. Clinical & Investigative Medicine 12(SUPPL 4): B98, 1989

Immunological studies in ulcerative colitis part 8 antibodies to colon antigen in patients with ulcerative colitis crohns disease and other diseases. Scandinavian Journal of Gastroenterology 12(6): 707-714, 1977

Evaluation of gut mucosal diamine oxidase activity in patients with food allergy and ulcerative colitis, idiopathic ulcerative colitis and crohns disease. Digestive Disease Week Abstracts & Itinerary Planner : Abstract No T1052, 2003

Cytomegalovirus Infection after Renal Transplantation: Occurrence, Clinical Features, and the Cutoff for Antigenemia in a University Hospital in Brazil. Infection & ChemoTherapy 49(4): 255-261, 2018

The immunology of ulcerative colitis and crohns disease clinical and humoral aspects. Kirsner, Joseph Boy G. Shorter (ed.). Inflammatory Bowel Disease. Xiii 465p. Illus. Lea And Febiger: Philadelphia, Pa., U.s.a. Isbn 0-8121-0480-3. 60-80, 1975