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Use of clotrimasol and nystatin in the treatment of mycotic mastitis in cows

Use of clotrimasol and nystatin in the treatment of mycotic mastitis in cows

Medycyna Weterynaryjna 58(10): 774-776

The therapeutic use of clotrimasol and nystatin in the treatment of mycotic udder inflammation in cows was determined in studies carried out between 1995-2001. During this period the presence of mycotic mastitis was observed in 367 udder quarters of cows undergoing treatment at the clinic, as well as in milk samples sent for testing by field doctors, mostly after ineffective, prolonged antibiotic therapy. 1% alcohol clotrimasol solution was used in the treatment. It had been diluted with distilled water before application, and did not exceed a dose of 100 mg/quarter/day. Nystatin suspended in a substrate used for commercial intra-udder preparations was also administered at a dose of 500 000 units/quarter/day. Both medicines were applied 2-4 times, usually every 24 hours. When necessary, clotrimasol therapy was repeated. The studies revealed that an average of 77,6% infected quarters were cured after a single course of clotrimasol therapy. The proportion of cured cows differed significantly in respective years, with the lowest proportion noted in the final two years of the study (64,4% and 57,1%). The preliminary results of treating mycotic udder infections using nystatin indicated that it was more effective in curing the illness than clotrimasol.

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Accession: 036014988

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