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Importance of high IgG anti-Toxoplasma gondii titers and PCR detection of T gondii DNA in peripheral blood samples for the diagnosis of AIDS-related cerebral toxoplasmosis a case-control study



Importance of high IgG anti-Toxoplasma gondii titers and PCR detection of T gondii DNA in peripheral blood samples for the diagnosis of AIDS-related cerebral toxoplasmosis a case-control study



The Brazilian Journal of Infectious Diseases 15(4): 356-359



Toxoplasmosis (CT) continues to cause significant morbidity and mortality in human immunodeficiency virus (HIV)-infected patients in Brazil. In clinical practice, the initial diagnosis is usually presumptive and alternative diagnosis tools are necessary. Our objective was to evaluate whether the detection of high titers of IgG anti-Toxoplasma gondii and T. gondii DNA in blood samples are associated with the diagnosis of CT. In this case-control study we included 192 patients with HIV-1 infection: 64 patients with presumptive CT (cases) and 128 patients with other diseases (controls). Blood samples to perform indirect immunofluorescense reaction (IFI) to detect anti-T. gondii IgG antibodies and.

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Accession: 036172407

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DOI: 10.1016/s1413-8670(11)70204-5


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