EurekaMag.com logo
+ Translate

Schizosaccharomyces pombehomologs of theSaccharomyces cerevisiaemitochondrial proteins Cbp6 and Mss51 function at a post-translational step of respiratory complex biogenesis


, : Schizosaccharomyces pombehomologs of theSaccharomyces cerevisiaemitochondrial proteins Cbp6 and Mss51 function at a post-translational step of respiratory complex biogenesis.

Complexes III and IV of the mitochondrial respiratory chain contain a few key subunits encoded by the mitochondrial genome. InSaccharomyces cerevisiae, fifteen mRNA-specific translational activators control mitochondrial translation, of which five are conserved inSchizosaccharomyces pombe. These include homologs of Cbp3, Cbp6 and Mss51 that participate in translation and the post-translational steps leading to the assembly of respiratory complexes III and IV. In this study we show that in contrast to budding yeast, Cbp3, Cbp6 and Mss51 fromS. pombeare not required for the translation of mitochondrial mRNAs, but fulfill post-translational functions, thus probably accounting for their conservation.S. cerevisiaecontains mRNA-specific activators controlling mitochondrial translation. Only a few of these factors seem conserved in the yeastS. pombeand in human. ConservedS. cerevisiaefactors have an additional rolee.g.in complex assembly We find that the homologs inS. pombefulfil only this complex assembly function. The complex assembly function is thus probably the ancestral one..

(PDF 0-2 workdays service)

Order PDF Full Text

Close
Close

Click here to order any other PDF Full Text


Accession: 036335909

Submit PDF Full Text: Here


Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:
Close
Close

Other references

Griffiths, M., 2011: Community perspective. Nursing Standard 1987) 25(42): 61-61

Joachim, C.; Rapenne, Génael., 2013: Molecule concept nanocars: chassis, wheels, and motors?. The design, synthesis, and running of a molecular nanovehicle on a surface assisted by proper nanocommunication channels for feeding and guiding the vehicle now constitute an active field of research and are no longer a nano-joke. In this Perspect...

Lyne, J.E.; Townsend, L.W.; Wilson, J.W., 2001: Critical need for a swingby return option for early manned Mars missions. Journal of Spacecraft and Rockets 35(6): 855-856

Chen, H.; Chu, G.; Cao, Z.; Liang, J.; Lu, J.; Zhou, G., 2010: Magnetic bead-based approach to monitoring of cigarette smoke-induced DNA oxidation damage and screening of natural protective compounds. Cigarette smoking can damage DNA and induce spontaneous mutagenesis or carcinogenesis. Here, we describe a novel strategy for in situ monitoring of cigarette smoke-induced DNA oxidation damage and offer a method for screening natural compounds tha...

Skelton, P. W., 1976: Functional morphology of the hippuritidae. The hippuritid shell consists of a small operculiform left valve capping a larger cylindrico-conical valve. There are 3 shell layers: an outer calcitic fibrillar prismatic layer, a crossed-lamellar aragonitic middle layer and a complex crossed-lam...

Chuang, F.R.ng; Lee, C.H.iung; Chen, J.B.r; Cheng, Y.F.; Yang, B.Y.u; Hsu, K.T.i; Wu, M.S.u, 2002: Extra-renal abscess in chronic hemodialysis patients. Aim: Infectious disease represents one of the major causes of morbidity and mortality in hemodialysis patients. Extra-renal abscess constitutes a specific form of infection. The aim of this study was to evaluate and analyze the clinical characteri...

Walcott, C., 1959: Behavior and vibration sensitivity in the spider. Anatomical Record, 134: 650-651

Hammacher, A.; Richardson, R.T.; Layton, J.E.; Smith, D.K.; Angus, L.J.; Hilton, D.J.; Nicola, N.A.; Wijdenes, J.; Simpson, R.J., 1998: The immunoglobulin-like module of gp130 is required for signaling by interleukin-6, but not by leukemia inhibitory factor. The transmembrane protein gp130 is a shared component of the receptor complexes for the interleukin-6 (IL-6)-type cytokines, which include IL-6, leukemia inhibitory factor (LIF) and oncostatin M (OSM). In addition to its role in the generation of...

Hurst R.D.; Mcdermott G.F.; Whiteside C.I., 1992: Vasopressor induced mesangial cell calcium signalling is increased by high glucose. Clinical & Investigative Medicine 15(4 SUPPL): A93

Sargant, N.N.; Smallwood, N.; Finlay, F., 2015: Sexual history taking: a dying skill?. Many adolescents are having sex and adolescents with life-limiting illnesses are no exception. It is therefore important for health care professionals to take a sexual history and provide advice about sexually transmitted diseases, unintended preg...