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Cell-specific intracellular anticancer drug delivery from mesoporous silica nanoparticles with pH sensitivity



Cell-specific intracellular anticancer drug delivery from mesoporous silica nanoparticles with pH sensitivity



Advanced Healthcare Materials 1(3): 321-325



A nanoreservoir for efficient intracellular anticancer drug delivery based on mesoporous silica nanoparticles end-capped with lactobionic acid-grafted bovine serum albumin is fabricated. It demonstrates great potential for both cell-specific endocytosis and intracellular pH-responsive controlled release of drugs. A possible endocytosis pathway/mechanism of the smart controlled drug release system is proposed.

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Accession: 036403472

Download citation: RISBibTeXText

PMID: 23184747

DOI: 10.1002/adhm.201100030


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