+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Effect of experimental feed additives on aflatoxin in milk of dairy cows fed aflatoxin-contaminated diets

Effect of experimental feed additives on aflatoxin in milk of dairy cows fed aflatoxin-contaminated diets

Journal of Animal Physiology and Animal Nutrition 97(4): 694-700

Three studies were conducted to determine the potential of experimental feed additives (EFAs), clays or non-digestible yeast oligosaccharides, to reduce milk aflatoxin (AFM1) concentrations in lactating Holstein cows consuming aflatoxin-contaminated diets. All studies included a pre-treatment period and a 2-week experimental period in a randomized block design. During the pre-treatment period, cows received a total mixed ration (TMR) with no aflatoxin contamination. During both experimental weeks, all cows were fed a TMR containing aflatoxin-contaminated corn. During experimental week 1, cows received no EFA's in the TMR, but EFA's were included in the TMR for the second experimental week. In studies 1 and 2, the experimental period consisted of 2 weeks each lasting 7 days with 12 cows per treatment. Aflatoxin M1 concentrations were analysed by HPLC for milk samples collected on days 5-7 and days 11-14. In various experiments, treatments included control (no EFA), 100 g/cow daily of experimental Lallemand(®) product, 10 g/cow daily of MTB-100(®) -2004, (Alltech, Inc.), 10 g/cow daily of MTB-100(®) -2006, (Alltech, Inc.), 10 g/cow daily of experimental Alltech(®) product (Alltech, Inc.) and 227 g/cow daily of Astra-Ben 20(®) (AB-20(®) ; Prince Agri Products, Inc.). In study 3, the experimental period of 2 weeks each lasting 8 days and milk samples were collected from day 4 to 8 and day 11 to 16. Milk samples from study 3 were analysed for AFM1 concentrations by ELISA. For all experiments, changes in AFM1 concentrations because of the addition of EFA's were calculated. Four of the five EFAs tested in this study had no significant effect on AFM1 concentrations. However, the addition of AB-20(®) resulted in a significant decrease in AFM1 concentrations (60.4%). In summary, the addition of AB-20(®) to the diet of cattle appears to be effective for significantly reducing AFM1 concentrations in the milk of cows fed an aflatoxin-contaminated diet.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 036443651

Download citation: RISBibTeXText

PMID: 22672473

DOI: 10.1111/j.1439-0396.2012.01311.x

Related references

Effect of feed additives on aflatoxin in milk of dairy cows fed aflatoxin-contaminated diets. Journal of Animal Science 84: 129-129, 2006

Effects of 3 sequestering agents on milk aflatoxin M1 concentration and the performance and immune status of dairy cows fed diets artificially contaminated with aflatoxin B1. Journal of Dairy Science 99(8): 6263-6273, 2016

Effects of Milk Yield, Feed Composition, and Feed Contamination with Aflatoxin B1 on the Aflatoxin M1 Concentration in Dairy Cows' Milk Investigated Using Monte Carlo Simulation Modelling. Toxins 8(10):, 2016

Effects of sepiolite addition to aflatoxin-contaminated diets on aflatoxin M1 residues in dairy cow milk. Journal of Animal Science 73(Suppl. 1): 283, 1995

Elimination of aflatoxin M1 in milk of lactating dairy cows after simultaneous feeding of adsorptive additives and aflatoxin B1 - studies in vivo and in vitro. Kieler Milchwirtschaftliche Forschungsberichte 52(2): 145-164, 2000

Responses of dairy cows to dietary aflatoxin: feed intake and yield, toxin content, and quality of milk of cows treated with pure and impure aflatoxin. Journal of Dairy Science 65(8): 1503-1508, 1982

Effects on aflatoxin m 1 residues in milk by addition of hydrated sodium calcium aluminosilicate to aflatoxin contaminated diet of dairy cows. American Journal of Veterinary Research 52(9): 1556-1559, 1991

Effect of some safe feed additives on growth performance, blood biochemistry, and bioaccumulation of aflatoxin residues of Nile tilapia fed aflatoxin-B 1 contaminated diet. Aquaculture 495: 27-34, 2018

Aflatoxin binders II: Reduction of aflatoxin M1 in milk by sequestering agents of cows consuming aflatoxin in feed. Mycopathologia 157(2): 233-241, 2004

Feed additives containing sequestrant clay minerals and inactivated yeast reduce aflatoxin excretion in milk of dairy cows. Journal of Dairy Science 102(7): 6614-6623, 2019

Effect of aflatoxin B1 contaminated rations on milk yield and aflatoxin M1 secretion in milk of Indian cows. Indian Journal of Animal Nutrition 16(4): 311-314, 1999

Responses of dairy cows to dietary aflatoxin, methods to eliminate aflatoxin M1 from milk and fate of aflatoxin M1 in Cottage cheese. Dissertation Abstracts International, B 42(11): 4346-4347, 1982

Effect of ammoniation of aflatoxin B1-contaminated cottonseed feedstock on the aflatoxin M1 content of cows' milk and hepatocarcinogenicity in the trout bioassay. Food and Chemical Toxicology 32(8): 707-715, 1994

Transfer of dietary aflatoxin B1 to milk aflatoxin M1 and effect of inclusion of adsorbent in the diet of dairy cows. Journal of Dairy Science 98(4): 2545-2554, 2015

Effect of adding a mycotoxin-sequestering agent on milk aflatoxin M₁ concentration and the performance and immune response of dairy cattle fed an aflatoxin B₁-contaminated diet. Journal of Dairy Science 95(10): 5901-5908, 2012