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Combined antimicrobial effect of essential oils and bacteriocins against foodborne pathogens and food spoilage bacteria

Mélanie Turgis; Khanh Dang Vu; Claude Dupont; Monique Lacroix

Food Research International 48(2)

2012


ISSN/ISBN: 0963-9969
DOI: 10.1016/j.foodres.2012.06.016
Accession: 036485491

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This study was achieved in order to determine the antimicrobial potential of six essential oils (EOs) (Origanum vulgare, Cinnamomum cassia, Brassica hirta, Thymus vulgaris, Satureja montagna, and Cymbopogon nardus) and four bacteriocins (nisin, pediocin, and two bacteriocins produced from our isolated Enterococcus faecium MT 14 and MT 162) against five pathogenic bacteria and two spoilage bacteria. The synergistic effect of combined antimicrobial agents on pathogenic bacteria was also evaluated. The antimicrobial activity was determined by evaluation of minimum inhibitory concentration (MIC) of the tested antimicrobial agents. Each agent was tested against seven bacterial foodborne pathogens (Bacillus cereus, Escherichia coli, Listeria monocytogenes, Salmonella typhimurium and Staphylococcus aureus) and food spoilage (Lactobacillus sakei and Pseudomonas putida) in 96-well microplate. The checkerboard technique was used to evaluate the possible synergistic effects between antimicrobial agents against each bacterium. The MIC value of 5ppm was obtained when C. cassia and O. vulgare EOs were tested against B. cereus, E. coli O157:H7, and L. sakei and when B. hirta EO was tested against P. putida and S. aureus. The combination of nisin with O. vulgare EO induced a synergistic effect against L. monocytogenes whereas the combination of nisin with T. vulgaris EO caused a synergistic effect against S. typhimurium. Pediocin caused a synergistic effect against E. coli O157: H7 when combined with the S. montagna EO. The combinations of EOs and bacteriocins can act synergistically or additionally to eliminate important foodborne pathogens and spoilage bacteria. This study demonstrated the potential of using different combinations of natural antimicrobial compounds to control foodborne pathogens effectively. Synergic inhibition effect of essential oils (EOs) and bacteriocins on food pathogens MT14b and MT162b are bacteriocins produced from new isolated Enterococcus faecium. Nisin plus Origanum vulgare EO caused a synergistic effect against L. monocytogenes. Pediocin plus Satureja montagna EO caused a synergistic effect on E. coli O157: H7. MT 14b plus Cinnamon cassia EO induced an additive effect on S. aureus.

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