+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Gender differences in association between metabolic syndrome and carotid intima media thickness

Gender differences in association between metabolic syndrome and carotid intima media thickness

Journal of Diabetes and Metabolic Disorders 11(1): 13

Metabolic syndrome (Mets) is a cluster of cardiovascular risk factors which can predicts cardiovascular disease (CVD). Carotid intima-media thickness (CIMT) is known as a surrogate measure of subclinical atherosclerosis and predictor of CVD. Although, it has shown the association between Mets and CIMT, this relation regarding sex differences is limited. We aimed to find out whether gender differences in this association. In this cross-sectional study, we recorded height, weight, waist circumference (WC), blood pressure, and lipid profiles. We used Mets; defined based on NCEP ATP III definition, and traditional cardiovascular risk factors; age, body mass index (BMI), WC, hyperlipidemia, and hypertension, in multivariate regression models which including;. The CIMT measurement < 0.73 or ≥0.73 mm was considered as low- or high risk to CVD. Overall, 150 subjects were enrolled to study that their ages were 36-75 years. The 47.3% of them (71 subjects) had Mets. CIMT was increased in Mets group compared non-Mets group (P = 0.001). In logistic regression analysis, a significant association was found between Mets and CIMT in women, but not in men (p = 0.002, and p = 0.364, respectively). After adjustment to age, WC, BMI, hypertension and hyperlipidemia, this association was significant just in women (p = 0.011) independent of WC, BMI, hyperlipidemia and hypertension. Our data showed that MetS is a stronger risk factor for subclinical atherosclerosis in women than in men. So, we suggest the assessment of CIMT along with definition Mets in middle-aged women could be lead to earlier detection of at risk individuals to CVD.

(PDF emailed within 0-6 h: $19.90)

Accession: 036649302

Download citation: RISBibTeXText

PMID: 23497686

DOI: 10.1186/2251-6581-11-13

Related references

Association between presence of the metabolic syndrome and its components with carotid intima-media thickness and carotid and femoral plaque area: a population study. Diabetology and Metabolic Syndrome 5: 44, 2013

Association between meat consumption and carotid intima-media thickness in Korean adults with metabolic syndrome. Journal of Preventive Medicine and Public Health 43(6): 486-495, 2011

Association between the intima-media thickness of the extracranial carotid arteries and metabolic syndrome in ethnic Kyrgyzs. Bmc Cardiovascular Disorders 18(1): 199, 2018

Association between nonalcoholic fatty liver disease and carotid intima-media thickness according to the presence of metabolic syndrome. Atherosclerosis 204(2): 521-525, 2008

Association of Anthropometric Measurements with Components of Metabolic Syndrome and Carotid Intima-Media Thickness in Young Healthy Taiwanese. Journal of Medical Ultrasound 20(4), 2012

Association of hyperandrogenemic and metabolic phenotype with carotid intima-media thickness in young women with polycystic ovary syndrome. Journal of Clinical Endocrinology and Metabolism 90(5): 2740-2746, 2005

Association of Hyperandrogenemic and Metabolic Phenotype with Carotid Intima-Media Thickness in Young Women with Polycystic Ovary Syndrome. Obstetric and Gynecologic Survey 61(2): 104-106, 2006

Association of aortic stiffness, carotid intima-media thickness and endothelial function with cardiovascular events in metabolic syndrome subjects. Blood Pressure 2019: 1-8, 2019

Association of insulin resistance with carotid intima-media thickness and brachial flow-mediated dilation in the subjects with metabolic syndrome. Atherosclerosis 252: E134-E135, 2016

The association between serum cystatin C and carotid intima-media thickness in metabolic syndrome patients with normal estimated glomerular filtration rate. Clinica Chimica Acta; International Journal of Clinical Chemistry 448: 170-173, 2016

Echocardiographic epicardial fat thickness is associated with carotid intima-media thickness in patients with metabolic syndrome. Echocardiography 28(8): 853-858, 2012

Gender differences in carotid intima-media thickness in patients with suspected coronary artery disease. American Journal of Cardiology 96(9): 1217-1222, 2005

Is there a gender-specific association between asthma and carotid intima media thickness in Swiss adolescents?. European Journal of Pediatrics 177(5): 699-707, 2018

Mesenteric fat thickness is an independent determinant of metabolic syndrome and identifies subjects with increased carotid intima-media thickness. Diabetes Care 29(2): 379-384, 2006

Gender, metabolic control and carotid intima-media-thickness in children and adolescents with type 1 diabetes mellitus. Wiener Klinische Wochenschrift 127(3-4): 116-123, 2015