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Differences in circadian time structure of diastolic blood pressure between diabetes mellitus and essential hypertension

, : Differences in circadian time structure of diastolic blood pressure between diabetes mellitus and essential hypertension. Diabetology & Metabolic Syndrome 4(1): 51-51

Abnormal circadian blood pressure patterns have been associated with cardiovascular disease in diabetes mellitus. We have described that the acrophase of diastolic blood pressure (DBP) registered in type 1 diabetes (T1D) patients was significantly earlier than normal and DBP ecphasia was more pronounced in patients with lower heart rate variability during deep breathing. The aim of this study was to compare the circadian rhythm characteristics of BP among different groups: normotensive (NT) control subjects, patients affected by T1D and type 2 diabetes (T2D), and patients with essential hypertension (HT).FindingsWe retrospectively evaluated ambulatory blood pressure monitoring records in 30 NT, 20 T1D, 20 T2D, 20 HT whose fasting plasma glucose and HbA1c were contemporaneously measured. The four groups were well-matched regarding age, gender, and BMI.Systolic blood pressure (SBP) and DBP midline-estimating statistic of rhythm were higher in T1D, T2D, and HT groups. DBP ecphasia was present only in the diabetic individuals: the acrophase of DBP occurred four hours earlier than normal in T1D group, whereas two hours earlier in T2D group. In a multiple regression analysis, only HbA1c and SBP acrophase were statistically significant correlates of DBP acrophase. People with diabetes mellitus, both type 1 and type 2, have their circadian acrophase of DBP occurring 2--4 hours earlier than normotensive and hypertensive subjects. Altered circadian timing of DBP, potential trigger of cardiovascular events, seems to be a distinguishing feature of diabetes mellitus and correlates with the previous 2--3 months of glycaemic control.

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Accession: 036655791

PMID: 23245213

DOI: 10.1186/1758-5996-4-51

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Junghans R.P.; Murphy E.C.Jr; Arlinghaus R.B., 1982: Electron microscopic analysis of ts 110 moloney mouse sarcoma virus a variant of wild type virus with 2 rna species containing large deletions. The ts110 Moloney (Mo) murine sarcoma virus (MuSV) codes for 2 viral-specific proteins termed P85 and P58. P85 is a gag-mos hybrid protein, whereas P58 is a product of the gag region. For ts110 Mo-MuSV to produce a gag-mos polyprotein, some deleti...

Scala P J.; Thiollet M.; Midavaine M.; Kher A.; Funck Brentano C.; Jaillon P.; Robert A.; Valty J., 1990: Deep venous thrombosis and left ventricular thrombosis prophylaxis by low molecular weight heparin in acute myocardial infarction. Haemostasis 20(6): 368-369

Konoplev, Eg; Sheremetev, Vg, 1977: Systems for the removal, processing and utilization of manure in the USA. Zhivotnovodstvo 5 92-94

Sudjarwo, Sri Agus; Hori, Masatoshi; Tanaka, Takeo; Matsuda, Yuzuru; Karaki, Hideaki, 1995: Coupling of the endothelin ET-A and ET-B receptors to Ca-2+ mobilization and Ca-2+ sensitization in vascular smooth muscle. Effects of endothelins on cytosolic Ca-2+ level ((Ca-2+)i) and contraction were examined in the swine pulmonary artery and vein. In the artery, endothelin-1 and endothelin-3, but not sarafotoxin S6c and IRL 1620 (300 nM each), induced transient in...

Mogielnicki, A., 1973: The health state of potatoes as affected by some cultural practices. Nowe rolnictwo: 15 22 (23) 7-8

Lieschke, G. J., 1996: G-CSF and GM-CSF in the management of acute marrow injury Focus on radiation-induced marrow aplasia. Macvittie, T J , Weiss, J F , Browne, D Advances in the Biosciences; Advances in the treatment of radiation injuries 1-13

Shipley W.U.; Kaufman D.S.; Heney N.M.; Griffin P.P.; Althausen A.F.; Prout G.R.Jr, 1990: The integration of chemotherapy radiotherapy and transurethral surgery in bladder sparing approaches for patients with invasive tumors. Splinter, T A W And H I Scher (Ed ) Progress in Clinical And Biological Research, Vol 353 Neoadjuvant Chemotherapy in Invasive Bladder Cancer; International Workshop, San Francisco, California, Usa, May 19-20, 1989 Xviii+241p Wiley-Liss: New York, New York, Usa; Chichester, England, Uk Illus 85-94

Wooten, Thomas L.; Lowrie, Charles T., 1993: Comparison of cerebrospinal fluid pressure in propofol- and thiopental-anesthetized eucapnic dogs. Cerebrospinal fluid pressure (CSF-p) was measured as part of the neurologic assessment of dogs with suspected intracranial disease. Because propofol has not been shown to cause an increase in intracranial pressure in humans, the authors examined i...

Musliner T.A.; Garner P.A.; Henderson L.O.; Herbert P.N., 1982: Radio immunoassay of apo lipo protein a ii. A double antibody radioimmunoassay was developed for apolipoprotein A-II (apo A-II), 1 of the 2 major apoproteins of human high density lipoproteins (HDL) [associated with predisposition to atherosclerosis development]. Apo A-II contains 2 identic...

Starzec Piotr, 1996: Dynamic testing of crystalline rocks. Publ - Chalmers Tekniska Hogskola, Geologiska Institutionen, B