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APTT prolongation and skin eruption possibly associated with lamotrigine monotherapy in a paediatric patient



APTT prolongation and skin eruption possibly associated with lamotrigine monotherapy in a paediatric patient



Epileptic Disorders 13(4): 452-455



We report the case of a six-year-old female with childhood absence epilepsy who developed combined aPTT prolongation, not corrected by normal plasma, and atypical skin eruption six months after initiating lamotrigine treatment with dose increment. Two weeks after lamotrigine withdrawal, the skin eruption disappeared and aPTT normalised. To our knowledge, this is the first report of aPTT prolongation possibly due to factor inhibitors associated with lamotrigine monotherapy.

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Accession: 036681055

Download citation: RISBibTeXText

PMID: 22258053

DOI: 10.1684/epd.2011.0470


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