+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Failure of normal development of central drive to ankle dorsiflexors relates to gait deficits in children with cerebral palsy



Failure of normal development of central drive to ankle dorsiflexors relates to gait deficits in children with cerebral palsy



Journal of Neurophysiology 109(3): 625-639



Neurophysiological markers of the central control of gait in children with cerebral palsy (CP) are used to assess developmental response to therapy. We measured the central common drive to a leg muscle in children with CP. We recorded electromyograms (EMGs) from the tibialis anterior (TA) muscle of 40 children with hemiplegic CP and 42 typically developing age-matched controls during static dorsiflexion of the ankle and during the swing phase of treadmill walking. The common drive to TA motoneurons was identified through time- and frequency-domain cross-correlation methods. In control subjects, the common drive consists of frequencies between 1 and 60 Hz with peaks at beta (15-25 Hz) and gamma (30-45 Hz) frequencies known to be caused by activity within sensorimotor cortex networks: this drive to motoneurons strengthens during childhood. Similar to this drive in control subjects, this drive to the least affected TA in the CP children tended to strengthen with age, although compared with that in the control subjects, it was slightly weaker. For CP subjects of all ages, the most affected TA muscle common drive was markedly reduced compared with that of their least affected muscle as well as that of controls. These differences between the least and most affected TA muscles were unrelated to differences in the magnitude of EMG in the two muscles but positively correlated with ankle dorsiflexion velocity and joint angle during gait. Time- and frequency-domain analysis of ongoing EMG recruited during behaviorally relevant lower limb tasks provides a noninvasive and important measure of the central drive to motoneurons in subjects with CP.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 036723094

Download citation: RISBibTeXText

PMID: 23136346

DOI: 10.1152/jn.00218.2012


Related references

Gait training facilitates central drive to ankle dorsiflexors in children with cerebral palsy. Brain 138(Pt 3): 589-603, 2015

Explosive Resistance Training Increases Rate of Force Development in Ankle Dorsiflexors and Gait Function in Adults With Cerebral Palsy. Journal of Strength and Conditioning Research 30(10): 2749-2760, 2016

Gait Training and Ankle Dorsiflexors in Cerebral Palsy. Pediatric Neurology Briefs 29(3): 22, 2015

Comparison of Spatiotemporal Gait Parameters between Children with Normal Development and Children with Diplegic Cerebral Palsy. Journal of Physical Therapy Science 26(9): 1317-1319, 2014

Phylogenetic and ontogenetic basis of normal and pathological gait development in children with cerebral palsy. Ortopedia Traumatologia Rehabilitacja 3(4): 462-466, 2001

Ankle-foot orthoses: effect on gait in children with cerebral palsy. Disability and Rehabilitation 24(7): 345-347, 2002

Ankle muscle activity during gait in children with cerebral palsy and equinovarus deformity. Archives of Physical Medicine and Rehabilitation 69(2): 115-117, 1988

Effect of ankle-foot orthoses on walking efficiency and gait in children with cerebral palsy. Journal of Rehabilitation Medicine 40(7): 529-534, 2008

Forefoot mobility in ankle and foot orthoses: effect on gait of children with cerebral palsy. Pediatric Physical Therapy 25(3): 331-337, 2013

Effect of ankle-foot orthoses on gait in children with cerebral palsy: A meta-analysis. Annals of Physical and Rehabilitation Medicine 59s(): E6-E6, 2016

Kinetic Relationships between the Hip and Ankle Joints during Gait in Children with Cerebral Palsy: A Pilot Study. Journal of Physical Therapy Science 26(5): 737-740, 2014

Effects of ankle-foot braces on medial gastrocnemius morphometrics and gait in children with cerebral palsy. Journal of Children's Orthopaedics 9(3): 209-219, 2015

The effects of ankle foot orthoses on energy recovery and work during gait in children with cerebral palsy. Clinical Biomechanics 27(3): 287-291, 2012

Acclimatization of the gait pattern to wearing an ankle-foot orthosis in children with spastic cerebral palsy. Clinical Biomechanics 30(6): 617-622, 2015

Increasing ankle strength to improve gait and function in children with cerebral palsy: a pilot study. Pediatric Physical Therapy 18(4): 266-275, 2006