+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Quantitative contrast ratio comparison between T1 (TSE at 1.5T, FLAIR at 3T), magnetization prepared rapid gradient echo and subtraction imaging at 1.5T and 3T



Quantitative contrast ratio comparison between T1 (TSE at 1.5T, FLAIR at 3T), magnetization prepared rapid gradient echo and subtraction imaging at 1.5T and 3T



Quantitative Imaging in Medicine and Surgery 3(3): 141-146



Creating contrast between normal anatomy and pathology is the main goal of imaging. Here we compare contrast ratios of enhancing brain lesions at 1.5T between T1 TSE, magnetization prepared rapid gradient echo (MPRAGE) and subtraction and at 3T between T1 FLAIR, MPRAGE and subtraction. Contrast ratio between enhancing lesions and normal contralateral brain was measured for above mentioned sequences during the same imaging session. A total of 27 exams on 25 patients were evaluated. A total of 90 enhancing brain lesions were utilized. Of these 46 were <5 mm diameter. Taking all lesions into account there was a small but statistically significant improvement in contrast ratio at 1.5T with MPRAGE compared to T1 TSE and at 3T for T1 FLAIR compared to MPRAGE. However, there was no statistically significant difference between these sequences for lesions 5 mm or less in diameter. However, subtraction provided a marked and statistically significant improvement in contrast ratio for both all lesions and including only lesions 5 mm or less in diameter. Our data indicate that for small lesions at 1.5T there is no significant difference in contrast ratio (CR) between T1 TSE and MPRAGE or at 3T between T1 FLAIR and MPRAGE despite the MPRAGE having the advantage of much thinner slices and a higher matrix. However, subtraction provided a markedly improved CR for all lesions at 1.5T and 3T regardless of lesion size. Subtraction should be considered for clinical use to improve detection of small or subtle enhancing lesions.

(PDF emailed within 1 workday: $29.90)

Accession: 036960787

Download citation: RISBibTeXText

PMID: 23833727


Related references

Magnetization prepared rapid gradient-echo (MP-RAGE) MR imaging of the liver: comparison with spin-echo imaging. Magnetic Resonance Imaging 9(4): 469-476, 1991

Usefulness of contrast-enhanced T1-weighted sampling perfection with application-optimized contrasts by using different flip angle evolutions in detection of small brain metastasis at 3T MR imaging: comparison with magnetization-prepared rapid acquisition of gradient echo imaging. Ajnr. American Journal of Neuroradiology 30(5): 923-929, 2009

Contrast-enhanced MR venography of the head using magnetization prepared rapid gradient echo imaging: comparison between head and body radiofrequency transmitter coil systems. Nihon Igaku Hoshasen Gakkai Zasshi. Nippon Acta Radiologica 64(1): 31-34, 2004

Identification of carotid non-hemorrhagic lipid-rich necrotic core by magnetization-prepared rapid acquisition gradient-echo imaging: Validation by contrast-enhanced T1 weighted imaging. Magnetic Resonance Imaging 63: 155-158, 2019

Normal structures in the intracranial dural sinuses: delineation with 3D contrast-enhanced magnetization prepared rapid acquisition gradient-echo imaging sequence. Ajnr. American Journal of Neuroradiology 23(10): 1739-1746, 2002

Implementation of a rapid inversion-prepared dual-contrast gradient echo sequence for quantitative dynamic contrast-enhanced magnetic resonance imaging of the human prostate. Magnetic Resonance Imaging 23(10): 983-990, 2005

Gadolinium-enhanced three-dimensional magnetization-prepared rapid gradient-echo (3D MP-RAGE) imaging is superior to spin-echo imaging in delineating brain metastases. Acta Radiologica 49(10): 1167-1173, 2008

Rapid T1 estimation using tagged magnetization-prepared gradient-echo MR imaging. Magnetic Resonance in Medicine 26(2): 377-385, 1992

Three-dimensional magnetization-prepared rapid gradient-echo imaging (3D MP RAGE). Magnetic Resonance in Medicine 15(1): 152-157, 1990

Shuffled magnetization-prepared multicontrast rapid gradient-echo imaging. Magnetic Resonance in Medicine 79(1): 62-70, 2017

Tracking motion with tagged rapid gradient-echo magnetization-prepared MR imaging. Journal of Magnetic Resonance Imaging 2(2): 155-163, 1992

Improved efficiency in 2DFT magnetization-prepared rapid gradient echo imaging: application to abdominal imaging. Magnetic Resonance in Medicine 25(1): 195-203, 1992

Comparison of the added value of contrast-enhanced 3D fluid-attenuated inversion recovery and magnetization-prepared rapid acquisition of gradient echo sequences in relation to conventional postcontrast T1-weighted images for the evaluation of leptomeningeal diseases at 3T. Ajnr. American Journal of Neuroradiology 31(5): 868-873, 2010

Non-contrast-enhanced magnetic resonance venography using magnetization-prepared rapid gradient-echo (MPRAGE) in the preoperative evaluation of living liver donor candidates: Comparison with conventional computed tomography venography. European Journal of Radiology 90: 89-96, 2018

Optimization of white-matter-nulled magnetization prepared rapid gradient echo (MP-RAGE) imaging. Magnetic Resonance in Medicine 73(5): 1786-1794, 2016