+ Translate
+ Most Popular
Advantages and disadvantages of bordeaux mixture and of lime-sulphur used on apples in the growing season
Observations on the Umaria marine bed
10 years of hearing conservation in the Royal Air Force
Chocolate crumb - dairy ingredient for milk chocolate
Effect of daily gelatin ingestion on human scalp hair
Comparison of rice bran and maize bran as feeds for growing and fattening pigs
The composition of pampas-grass (Cortaderia argentea.)
The Accraian Series:
The mechanism of the Liebermann-Burchard reaction of sterols and triterpenes and their esters
Cerebrovascular Doppler ultrasound studies (cv-Doppler)
Toria: PT-303 - first national variety
Hair growth promoting activity of tridax procumbens
Productivity of Pekin x Khaki Campbell ducks
A stable cytosolic expression of VH antibody fragment directed against PVY NIa protein in transgenic potato plant confers partial protection against the virus
Solar treatment of wheat loose smut
Swimmers itch in the Lake of Garda
Bactofugation and the Bactotherm process
The effects of prefrontal lobotomy on aggressive behavior in dogs
Visual rating scales for screening whorl-stage corn for resistance to fall armyworm
Breakdown of seamounts at the trench axis, viewed from gravity anomaly
Kooken; pennsylvania's toughest cave
Recovery of new dinosaur and other fossils from the Early Cretaceous Arundel Clay facies (Potomac Group) of central Maryland, U.S.A
Zubor horny (Bison bonasus) v prirodnych podmienkach Slovensku
The extended Widal test in the diagnosis of fevers due to Salmonella infection
Hair of the american mastodon indicates an adaptation to a semi aquatic habitat

Neural correlates of reward and loss sensitivity in psychopathy

Neural correlates of reward and loss sensitivity in psychopathy

Social Cognitive and Affective Neuroscience 9(6): 794-801

ISSN/ISBN: 1749-5016

PMID: 23552079

DOI: 10.1093/scan/nst054

Psychopathy is a personality disorder associated with callous and impulsive behavior and criminal recidivism. It has long been theorized that psychopaths have deficits in processing reward and punishment. Here, we use structural and functional magnetic resonance imaging to examine the neural correlates of reward and loss sensitivity in a group of criminal psychopaths. Forty-one adult male prison inmates (n = 18 psychopaths and n = 23 non-psychopaths) completed a functional magnetic resonance imaging task involving the gain or loss of money. Across the entire sample of participants, monetary gains elicited robust activation within the ventral striatum (VS). Although psychopaths and non-psychopaths did not significantly differ with respect to overall levels of VS response to reward vs loss, we observed significantly different correlations between VS responses and psychopathy severity within each group. Volumetric analyses of striatal subregions revealed a similar pattern of correlations, specifically for the right accumbens area within VS. In a separate sample of inmates (n = 93 psychopaths and n = 117 non-psychopaths) who completed a self-report measure of appetitive motivation, we again found that the correlation with psychopathy severity differed between groups. These convergent results offer novel insight into the neural substrates of reward and loss processing in psychopathy.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 037271420

Download citation: RISBibTeXText

Related references

Different neural correlates of reward expectation and reward expectation error in the putamen and caudate nucleus during stimulus-action-reward association learning. Journal of Neurophysiology 95(2): 948-959, 2006

Altered neural correlates of reward and loss processing during simulated slot-machine fMRI in pathological gambling and cocaine dependence. Drug and Alcohol Dependence 145: 77-86, 2014

Interdependent Neural Correlates of Reward and Punishment Sensitivity During Rewarded Action and Inhibition of Action. Cerebral Cortex 30(3): 1662-1676, 2020

Neural correlates of RDoC reward constructs in adolescents with diverse psychiatric symptoms: A Reward Flanker Task pilot study. Journal of Affective Disorders 216: 36-45, 2017

Neural, behavioural and real-life correlates of social context sensitivity and social reward learning during interpersonal interactions in the schizophrenia spectrum. Australian and New Zealand Journal of Psychiatry 2021: 48674211010327, 2021

Neural Processing of Calories in Brain Reward Areas Can be Modulated by Reward Sensitivity. Frontiers in Behavioral Neuroscience 9: 371, 2015

Sex differences in neural responses to reward and the influences of individual reward and punishment sensitivity. Bmc Neuroscience 22(1): 12, 2021

S271. Neural Activation to Monetary Reward is Associated With Amphetamine Reward Sensitivity. Biological Psychiatry 83(9): S453-S454, 2018

Individual differences in sensitivity to reward and punishment and neural activity during reward and avoidance learning. Social Cognitive and Affective Neuroscience 10(9): 1219-1227, 2015

Neural activation to monetary reward is associated with amphetamine reward sensitivity. Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology 43(8): 1738-1744, 2018

The neural correlates of moral decision-making in psychopathy. Molecular Psychiatry 14(1): 5-6, 2009

Investigating the neural correlates of psychopathy: a critical review. Molecular Psychiatry 16(8): 792-799, 2011

Functional neural correlates of psychopathy: a meta-analysis of MRI data. Translational Psychiatry 10(1): 133, 2020

Neural correlates of error-related learning deficits in individuals with psychopathy. Psychological Medicine 40(9): 1559-1568, 2010

A review of psychopathy and Cluster B personality traits and their neural correlates in female offenders. Biological Psychology 148: 107740, 2019