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A comparative study of the effects of hydrocortisone and adrenalin on blood glucose level and liver glycogen content in the frog Rana tigrina and the lizard Uromastix hardwickii

Ahmad, MM.; Alim, B.

Biologia (Lahore) 282: 255-262

1982


Accession: 037576391

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Changes in the blood glucose and liver glycogen of R. tigrina and U. hardwickii were studied after administration of hydrocortisone and adrenaline epinephrine, E . Hydrocortisone 25 mg/kg was administered i.m. in frogs and lizards for 3 days and the animals were sacrificed on the 4th day. A hyperglycemia and significant rise in liver glycogen was observed. In U. hardwickii the intensity of hyperglycemia and elevation of the liver glycogen was greater as compared to frogs. A hyperglycemic response to E at a dose of 0.5 ml/animal was also observed in frogs and lizards. Blood glucose responses were maximal at 1 h. E induced elevation of liver glycogen in these animals. Similarly, the intensity of hyperglycemia and elevation of liver glycogen in Uromastix was again greater as compared to frogs after E administration.

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