EurekaMag
+ Translate
+ Most Popular
Gaucher's disease;thirty-two years experience at Siriraj Hospital
A study of Macrobathra Meyrick from China (Lepidoptera, Cosmopterigidae)
First occurrence in ores of tetragonal chalcocite
Effects of trace element nutrition on sleep patterns in adult women
N.Z. range management guidelines. 2. Design of grazing management systems for tussock country
A case of lipoma of the esophagus
A revision of world Acanthosomatidae (Heteroptera: Pentatomidae): keys to and descriptions of subfamilies, tribes and genera, with designation of types
Life history of the coronate scyphozoan Linuche unguiculata (Swartz, 1788)
Perceptual restoration of obliterated sounds
Mutagenicity studies on two chromium(III) coordination compounds
The formation of the skeleton. I. Growth of a long bone. 1st appearance of a center of calcification
Leucopenia and abnormal liver function in travellers on malaria chemoprophylaxis
The joint commission: four key root causes loom large in sentinel event data
Treatment of vitiligo with topical 15% lactic acid solution in combination with ultra violet-A
Behaviour of dairy cows within three hours after feed supply: I. Influence of housing type and time elapsing after feed supply
Observations of the propagation velocity and formation mechanism of burst fractures caused by gunshot
Management and control of patients with type 2 diabetes mellitus in Lebanon: results from the International Diabetes Management Practices Study (IDMPS)
The diet composition and nutritional knowledge of patients with anorexia nervosa
Physoporella croatica Herak, 1958 of the Slovak karst Anisian (Slovakia, the West Carpathians Mts.)
Bright lights, big noise. How effective are vehicle warning systems?
Ein Plesiosaurier-Rest mit Magensteinen aus mittlerem Lias von Quedlinburg
Incidence of Chlamydia trachomatis in patients with sterility
Monster soup: the microscope and Victorian fantasy
Preliminary tests with residual sprays against poultry lice
Duration of the life of plants in phylogeny

Capillary permeability to interstitial microinjections of macromolecules and influence of capillary hydrostatic pressure on endothelial ultrastructure


Capillary permeability to interstitial microinjections of macromolecules and influence of capillary hydrostatic pressure on endothelial ultrastructure



Acta Physiologica Scandinavica. Supplementum 463: 45-50



ISSN/ISBN: 0302-2994

PMID: 89786

The transcapillary flux of horseradish peroxidase (HRP, mol. diam. 50--60 A) and ferritin (mol. diam. 110--120 A), microinjected interstitially into the biceps femoris muscle of rats, was analyzed in the electron microscope. From 1 min postinjection HRP was observed to occupy endothelial plasmalemmal vesicles in all positions to be expected if a vesicular transendothelial transport of material occurs in the interstitium-to-lumen direction. Permeation of HRP through the intercellular clefts of the endothelium could not be demonstrated unequivocally. The periendothelial basement membrane appeared to constitute a significant permeability barrier against ferritin. The endothelial ultrastructure in muscle capillaries was analysed morphometrically after artificial perfusions of rat hindquarters at venous outflow pressures of -4 cm H2O and +10 cm H2O. In the "high pressure" material the endothelium was thinner and the frequency of vesicles open towards the interstitium was lower than after perfusion at low outflow pressure. The findings may indicate that net transendothelial transport via vesicles varies with hemodynamics.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 038918562

Download citation: RISBibTeXText

Related references

Renal interstitium ultrastructure and capillary permeability part 2 electron microscopic studies on peri tubular capillary permeability using protein tracers with a comment to the pore theory of capillary permeability. Cytobiologie 10(2): 185-198, 1975

The Influence of Intermittently Increased Hydrostatic Pressure on the Permeability of the Capillary Wall in Frogs. Dermatologica 128: 81-84, 1964

Isoproterenol reduces hydrogen peroxide-induced increases in lung weight by decreasing endothelial protein permeability, water conductance, and capillary hydrostatic pressure. FASEB Journal 10(3): A107, 1996

The relation of Hydrostatic Pressure to the Gradient of Capillary Permeability. Journal of Experimental Medicine 55(2): 203-221, 1932

Increased glomerular capillary permeability to albumin by small elevations of hydrostatic pressure in isolated perfused rat kidneys. Journal of the American Society of Nephrology 2(3): 519, 1991

Evidence for interaction between capillary endothelial cells and pericytes in the regulation of capillary permeability. Clinical Research 34(2): 547A, 1986

The influence of hydrostatic pressure and colloid osmotic pressure on fluid transfer across the capillary membranes. Moyer and Fuchs Eds Edema Mechanisms and management 3-6, 1960

Capillary pressure and endothelial cell ultrastructure. Bibliotheca Anatomica 1977(15 Pt 1): 528-530, 1977

Influence of capillary permeability on interstitial fluid composition. Journal of Molecular and Cellular Cardiology 15(Supp-S1): 18-18, 1983

Capillary pressure pre capillary and post capillary resistance capillary filtration coefficient during angiotensin infusion in isolated dog hind limb. Physiologist 13(3): 238, 1970

Capillary pressure pre capillary and post capillary resistance capillary filtration coefficient during levarterenol infusion in isolated dog hind limb. Clinical Research 17(3): 513, 1969

Capillary filtration coefficient capillary pressure pre capillary and post capillary resistance during isoproterenol cardio vasc infusion in isolated dog hind limb abstract. Federation Proceedings 28(2): 645, 1969

The effect of micro-heterogeneity and capillary number on capillary pressure and relative permeability curves of soils. Geoderma 148.1, 2008

Co-sequestration of SO2 with supercritical CO2 in carbonates: An experimental study of capillary trapping, relative permeability, and capillary pressure. Advances in Water Resources 77: 44-56, 2015

Increased capillary pressure induced by venous occlusion does not increase capillary permeability in healthy subjects. European Journal of Clinical Investigation 29(Suppl 1): 76, 1999