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Glutamine synthetase of Klebsiella aerogenes: properties of glnD mutants lacking uridylyltransferase


, : Glutamine synthetase of Klebsiella aerogenes: properties of glnD mutants lacking uridylyltransferase. Journal of Bacteriology 134(2): 562-568

The glnD mutation of Klebsiella aerogenes is cotransducible by phage P1 with pan (requirement for pantothenate) and leads to a loss of uridylytransferase and uridylyl-removing enzyme, components of the glutamine synthetase adenylylation system. This defect results in an inability to deadenylylate glutamine synthetase rapidly and in a requirement for glutamine for normal growth. Suppression of the glnD mutation are located at the glutamine synthetase structural gene glnA.


Accession: 038942568

PMID: 26659

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Related references

Reuveny Z.; Foor F.; Magasanik B., 1979: Regulation of glutamine synthetase in klebsiella aerogenes mutants lacking adenylyl transferase. Abstracts of the Annual Meeting of the American Society for Microbiology (79): 165

Reuveny, Z.; Foor, F.; Magasanik, B., 1981: Regulation of glutamine synthetase by regulatory protein PII in Klebsiella aerogenes mutants lacking adenylyltransferase. A mutation of Klebsiella aerogenes causing production of an altered PII regulatory protein which stimulates overadenylylation of glutamine synthetase and also prevents its derepression was combined with mutations abolishing the activity of adenyly...

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Streicher S.L.; Tyler B.M., 1976: New methods for the purification of glutamine synthetase from klebsiella aerogenes indicate the presence of a glutamine synthetase dna complex in the bacterial cell. Federation Proceedings 35(7): 598

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