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Glutamine synthetase of Klebsiella aerogenes: properties of glnD mutants lacking uridylyltransferase



Glutamine synthetase of Klebsiella aerogenes: properties of glnD mutants lacking uridylyltransferase



Journal of Bacteriology 134(2): 562-568



The glnD mutation of Klebsiella aerogenes is cotransducible by phage P1 with pan (requirement for pantothenate) and leads to a loss of uridylytransferase and uridylyl-removing enzyme, components of the glutamine synthetase adenylylation system. This defect results in an inability to deadenylylate glutamine synthetase rapidly and in a requirement for glutamine for normal growth. Suppression of the glnD mutation are located at the glutamine synthetase structural gene glnA.

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Accession: 038942568

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PMID: 26659



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