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Interferon induced in the hamster by subunits of "Nocardia": essay of protection against rabies



Interferon induced in the hamster by subunits of "Nocardia": essay of protection against rabies



Annales de Microbiologie 130b(2): 263-269



Lipid-free cells of Nocardia opaca and a cell extract (NWSM) are interferon inducers in syrian hamsters: peak interferon appears 2 h after injection as compared to 8 h in the case of interferon induced by inactivated NDV virus. The interferon induced by Nocardia product is inactivated by a treatment for 30 min at 56 degrees C or 24 h at pH 2: NDV-induced interferon is more stable under these conditions. Hamsters inoculated with NWSM before and after infection with rabies virus are partially protected: their survival time is slightly increased.

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Accession: 038951362

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PMID: 43690


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