EurekaMag.com logo
+ Site Statistics
References:
48,252,460
Abstracts:
22,798,453
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Oxygen availability during hypothermic cardiopulmonary bypass


, : Oxygen availability during hypothermic cardiopulmonary bypass. Critical Care Medicine 5(3): 154-158

Oxygen availability during cardiopulmonary bypass was assessed in 22 patients under hypothermic and relatively normothermic conditions. The patients were divided into two groups, 17 of whom received ACD blood and 5, CPD blood. The mean P50 for all patients fell from a preoperative value of 25.9 +/- 2.4 (SD) to 15.6 +/- 2.1 during hypothermia confirming a leftward shift of the oxyhemoglobin dissociation curve. Oxygen uptake, calculated from a-v oxygen content differences (avDO2) and flow, was significantly lower during hypothermic bypass (65 +/- 27 ml/min) than during rewarming (121 +/- 41 ml/min). The increase in oxygen affinity during hypothermia was influenced also by changes in acid base and 2,3-DPG concentrations, the changes being similar in both the ACD and CPD groups of patients. During rewarming, however, oxygen availability was increased in the CPD group presumably from significantly increased 2,3-DPG concentrations. A "functional" value of hemoglobin, based upon the effects of the shift of the oxyhemoglobin dissociation curve and, therefore, reflecting the true capacity of hemoglobin to unload oxygen at the tissue level, was calculated. During the hypothermic phase of bypass, this functional hemoglobin was only 4.2 g/100 ml blood, suggesting that, in spite of reduced metabolic demands, oxygenation reserves are minimal.

(PDF 0-2 workdays service)

Order PDF Full Text

Close
Close

Click here to order any other PDF Full Text


Accession: 038964445

PMID: 16730

PDF Full Text: Submit


Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:
Close
Close

Other references

Coleman, R.; Trembath, R. C.; Harper, J. I., 1997: Genetic studies of atopy and atopic dermatitis. Atopy and the atopic disorders are likely to result from multifactorial inheritance, with interaction between genetic and environmental factors. It has been proposed that at least two major mechanisms, non-antigen specific (total IgE levels) and a...

Castell, A.; Johansson, P.; Unge, T.; Jones, T.Alwyn.; Bäckbro, K., 2005: Rv0216, a conserved hypothetical protein from Mycobacterium tuberculosis that is essential for bacterial survival during infection, has a double hotdog fold. The Mycobacterium tuberculosis genome contains about 4000 genes, of which approximately a third code for proteins of unknown function or are classified as conserved hypothetical proteins. We have determined the three-dimensional structure of one o...

Douenel, C., 1988: Nematodes-bacteria, an association effective in the control of insects. With special reference to studies in France, the potential of entomophilic nematodes, in association with symbiotic bacteria in their guts, as biological control agents against insect pests of agriculture is discussed. Special attention is paid to...

Pagano, J. S.; Crichlow, R. W.; Jensen, F.; Cornog, J. L.; Ravdin, R. G.; Koprowski, H., 1964: Growth of Simian virus40-transformed human cells in homologous hosts. Abstract only.

Anderson, G. D., 1967: Promising pasture plants for northern Tanzania IV Legumes, grasses and grass/legume mixtures. The early performance of different legumes and grasses and grass/legume mixtures was observed and assessed in terms of dry-matter and crude-protein production in small plots at Tengeru. Of the legumes, Hairy Peruvian, Hunter River and Saladina luc...

Watanabe S., 1987: Phytogeography of the forest stratification a case of the nopporo natural forest sapporo district hokkaido japan. From the floristic regional point of view, horizontal distribution in Hokkaido belongs to "Sino-Japanese Region". Fagus cremata, characteristic species of Japanese temperature zone, distributes up to the Kuromatsunai Depression in south-...

Franchini, C.; Noja, F.C.; Corbo, F.; Lentini, G.; Tortorella, V.; Bartolini, A.; Ghelardini, C.; Matucci, R.; Giotti, A., 1993: Stereoselectivity in central analgesic action of tocainide and its analogs. The antiarrhythmic drug tocainide (5a) and some related chiral alpha-amino and alpha-amino anilides (5b-e) were synthesized in optically active form. The antinociceptive effects of the different stereoisomers of these compounds were examined and i...

Boudreau, C.; Heath, E.; Seuntjens, J.; Ballivy, O.; Parker, W., 2005: IMRT head and neck treatment planning with a commercially available Monte Carlo based planning system. The PEREGRINE Monte Carlo dose-calculation system (North American Scientific, Cranberry Township, PA) is the first commercially available Monte Carlo dose-calculation code intended specifically for intensity modulated radiotherapy (INMT) treatment...

Montgomery L.D.; Williams B.A., 1976: Variation of fore arm hand and finger blood flow indices with ambient temperatures. Federation Proceedings 35(3): 720

Parker, R. C.; Connor, J. M., 1979: Estimates of consumer loss due to monopoly in the US food-manufacturing industries. Three independent methodological approaches and data sets are used to estimate the consumer loss due to monopoly in the US food-manufacturing industries for 1975. They include estimates (a) built up from previously estimated components of consumer...