+ Site Statistics
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Parasympathicolytic drugs in treatment of obstructive lung diseases

, : Parasympathicolytic drugs in treatment of obstructive lung diseases. Deutsche Medizinische Wochenschrift 104(31): 1098-1104

In order to investigate the effect of ipratropium bromide in antigen induced bronchial obstruction 8 series of investigations were performed in patients with extrinsic asthma using bronchial provocation tests. The broncholytic effect of ipratropium bromide (0.1 and 0.25 mg in 1 ml solution) was significantly lower when compared with fenoterol and salbutamol and not clearly distinct from untreated controls, when airway resistance, thoracic gas volume and specific airway resistance were measured. No correlation of the effect of ipratropium bromide with bronchial reactivity to histamine, basal values and antigen induced obstruction as well as corticosteroid dependency could be ascertained. Increase of dosage did not lead to improved effectiveness. In contrast protective application of ipratropium bromide before antigen inhalation led to prevention of obstructions did disodium cromoglycate. It is concluded that regular prophylactic application of ipratropium bromide is more effective than bronchospasmolytic application. All forms of obstructive pulmonary disease are thus an indication for parasympathicolytic drugs provided they are used regularly.

(PDF 0-2 workdays service)

Order PDF Full Text


Click here to order any other PDF Full Text

Accession: 038964872

PMID: 37060

PDF Full Text: Submit

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Other references

Denis, Michel; Cocude, Marguerite, 1992: Structural properties of visual images constructed from poorly or well-structured verbal descriptions. Previous research has found a linear relation between distance and scanning times for spatial configurations when the spatial configurations were learned perceptually and when they were constructed from well-structured verbal descriptions. The cur...

Long, M.; Goldsmith, H.L.; Tees, D.F.; Zhu, C., 1999: Probabilistic modeling of shear-induced formation and breakage of doublets cross-linked by receptor-ligand bonds. A model was constructed to describe previously published experiments of shear-induced formation and breakage of doublets of red cells and of latexes cross-linked by receptor-ligand bonds (Tees et al. 1993. Biophys. J. 65:1318-1334; Tees and Goldsm...

Uzmann, J. R., 1967: Juvenile Ascarophis in the American lobster, Homarus americanus. J Parasitol 53(1): 218

Meerson, F.Z.; Kapelko, V.I., 1975: The significance of the interrelationship between the intensity of the contractile state and the velocity of relaxation in adapting cardiac muscle to function at high work loads. Journal of Molecular and Cellular Cardiology 7(11): 793-806

Wright, JP.; Fisher, DB.; Mittler, TE., 1985: Measurement of aphid feeding rates on artificial diets using 3H-inulin. Radioactivity of the honeydew droplets excreted by young apterous adults of the green peach aphid, Myzus persicae, fed on an artificial diet containing 3H-inulin was a reliable measure of the volume of food ingested by the insects, since almost no...

Bucy, R. Pat; Kilby, J. Michael, 2001: Perspectives on inducing efficient immune control of HIV-1 replication: A new goal for HIV therapeutics?. Objectives: A goal for long-term therapy of HIV infection is immune control of virus replication rather than the somewhat unrealistic aim of complete viral elimination. This paper will review the evidence that the control of viral infection can be...

Krivin, B. G., 1960: Effect of ecology on the development of stolbur. The effect of meteorological conditions and agrotechnical measures on the development of the disease is considered. A complex of agricultural measures is recommended for combatting stolbur.

Makitalo, Kari; Hyvonen, Juha, 2004: Late-summer soil water content on clear-cut reforestation areas two decades after site preparation in Finnish Lapland. Site preparation has been widely used on reforestation areas in Finnish Lapland due to the high soil moisture and low temperature. The long-term effect of site preparation on soil volumetric water content was studied in ploughed ridges and the unt...

Lapin, B. A.; Adzhigitov, F. I.; Yakovleva, L. A., 1966: Oncogenic properties of human adenovirus type 12 for some mammals. The study of oncogenic activity of adenovirus type 12 confirmed the data on a high blastogenic activity of this virus for Syrian hamsters. Along with this the oncogenic proper-ties of this virus were recorded for 2 strains of rats: Wistar and Augu...

Griffin, H.E.; Meunier, L.D., 1990: Eosinophilic enteritis in a specific-pathogen-free cat. Moderate to severe, chronic, segmental eosinophilic enteritis was diagnosed histopathologically in a 2-year-old, specific-pathogen-free cat. Peripheral eosinophilia was not observed, although eosinophilic infiltrates were found in mesenteric lymph...