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Specificity of thyroid hormone synthesis. The role of thyroid peroxidase

, : Specificity of thyroid hormone synthesis. The role of thyroid peroxidase. Biochimica et Biophysica Acta 540(1): 73-82

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Saller, B.; Hörmann, R.; Mann, K., 1991: Heterogeneity of autoantibodies against thyroid peroxidase in autoimmune thyroid disease: evidence against antibodies directly inhibiting peroxidase activity as regulatory factors in thyroid hormone metabolism. The close relationship between thyroid microsomal antigen and thyroid peroxidase (TPO) is now well established. The present study evaluates the significance of autoantibodies against TPO (anti-TPO-Abs) in the various forms and stages of autoimmune...

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Sugawara, M.; Hagen, G.A., 1982: Thyroid hormone formation catalyzed by human thyroid peroxidase: a new and physiological measurement of thyroid peroxidase. This report describes a method for measurement of TPO [thyroid peroxidase] activity by the amount of thyroid hormone production. Thyroid hormone formation was accomplished by incubating purified iodine-poor Tg [triiodothyronine] with human TPO for...

Maurizis, J.C.; Marriq, C.; Michelot, J.; Rolland, M.; Lissitzky, S., 1979: Thyroid peroxidase-induced thyroid hormone synthesis in relation to thyroglobulin structure. Febs Letters 102(1): 82-86

Dème, D.; Fimiani, E.; Pommier, J.; Nunez, J., 1975: Free diiodotyrosine effects on protein iodination and thyroid hormone synthesis catalyzed by thyroid peroxidase. Free diiosotyrosine exerts two opposite effects on the reactions catalyzed by thyroid peroxidase, thyroglobulin iodination and thyroid hormone formation. 1. Inhibition of thyroglobulin iodination catalyzed by thyroid peroxidase was observed when f...

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Nakamura, M.; Ohtaki, S., 1990: Mechanism of thyroid hormone synthesis by thyroid peroxidase. Tanpakushitsu Kakusan Koso. Protein, Nucleic Acid, Enzyme 35(5): 814-824

Deme D.; Pommier J., 1977: Specificity of thyroid hormone synthesis the role of the enzyme. Annales d'Endocrinologie 38(5): 40A

Köhrle, J.; Oertel, M.; Gross, M., 1992: Selenium supply regulates thyroid function, thyroid hormone synthesis and metabolism by altering the expression of the selenoenzymes Type I 5'-deiodinase and glutathione peroxidase. Selenium supply appears to be insufficient in several regions of Europe as indicated by analysis of plasma and tissue selenium content and measurements of selenium dependent glutathione peroxidases (GPx). Selenium deficiency alters both thyroid ho...

Hayakawa N.; Hirakawa S.; Nakai H.; Yamahara S.; Ota Z., 1991: Expression of thyroid peroxidase on follicular cells in mini organ culture of thyroid and influence of thyroid autoantibodies on thyroid peroxidase activity. Japanese Journal of Clinical Electron Microscopy 24(5-6): 544-545