EurekaMag.com logo
+ Site Statistics
References:
52,654,530
Abstracts:
29,560,856
PMIDs:
28,072,755
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

6-Mercaptopurine-related leucopenia and in vivo xanthine oxidase activity



6-Mercaptopurine-related leucopenia and in vivo xanthine oxidase activity



Lancet 2(8511): 869-870




(PDF emailed within 0-6 h: $19.90)

Accession: 039022704

Download citation: RISBibTeXText

PMID: 2876319

DOI: 10.1016/S0140-6736(86)92911-9



Related references

Nature and position of functional group on thiopurine substrates influence activity of xanthine oxidase - Enzymatic reaction pathways of 6-mercaptopurine and 2-mercaptopurine are different. Biochemistry (Moscow) 72(2): 170-177, 2007

In vitro oxidative metabolism of 6-mercaptopurine in human liver: insights into the role of the molybdoflavoenzymes aldehyde oxidase, xanthine oxidase, and xanthine dehydrogenase. Drug Metabolism and Disposition: the Biological Fate of Chemicals 42(8): 1334-1340, 2015

Nitrite reductase activity of rat and human xanthine oxidase, xanthine dehydrogenase, and aldehyde oxidase: evaluation of their contribution to NO formation in vivo. Biochemistry 54(3): 685-710, 2015

In vitro effects of corticosteroids, DDT, and 4, 9-dichlorodibenzodioxin on rat liver xanthine oxidase activity. Interactions between xanthine oxidase and cytochrome P450 in rat liver in vivo. Biochemistry. Biokhimiia 65(8): 972-975, 2000

Possible association of xanthine dehydrogenase/xanthine oxidase activity with nitric oxide in vivo. Nephron 75(1): 123-124, 1997

In vitro study of 6-mercaptopurine oxidation catalysed by aldehyde oxidase and xanthine oxidase. Drug Metabolism and Pharmacokinetics 22(4): 299-306, 2007

NADH oxidase activity of rat liver xanthine dehydrogenase and xanthine oxidase-contribution for damage mechanisms. Free Radical Research 39(9): 979-986, 2005

Xanthine oxidase as a source of superoxide radicals in vivo repression and induction of the xanthine oxidase and superoxide dismutase activities in mouse liver upon administration of allopurinol. Studia Biophysica 113(1-2): 95-104, 1986

A xanthinuric family--the proposita having immunologically reactive xanthine oxidase but no xanthine oxidase activity. Advances in Experimental Medicine and Biology 309a: 369-372, 1991

6-Mercaptopurine-induced histopathological changes and xanthine oxidase expression in rat placenta. Journal of Toxicological Sciences 37(3): 607-615, 2012

Potentiation of the inhibition of xanthine oxidase by a combination of 6-mercaptopurine and 6-thioguanine. Experientia 37(2): 175-176, 1981

Rat and human liver xanthine oxidase and xanthine dehydrogenase: NADH oxidase activity. 2007

The use of xanthine oxidase for a specific and sensitive fluorimetric determination of 6-mercaptopurine in serum. Biochemical Medicine 32(3): 303-310, 1984

Studies on the mechanism of action of 6-mercaptopurine. Interaction with copper and xanthine oxidase. Biochemical Journal 193(3): 799-803, 1981

The use of xanthine oxidase ec 1.2.3.2 for a specific and sensitive fluorometric determination of 6 mercaptopurine in serum. Biochemical Medicine 32(3): 303-310, 1984