+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

A case of superimposed renal lesions of IgA and membranous nephropathy with diabetic nephropathy

A case of superimposed renal lesions of IgA and membranous nephropathy with diabetic nephropathy

Nihon Jinzo Gakkai Shi 34(8): 931-938

A 64-yr-old man presented with diabetes mellitus, proteinuria, hypertension and moderate renal dysfunction. Renal biopsy revealed diabetic glomerulosclerosis (diffuse lesion), IgA nephropathy and membranous nephropathy (stage 2). Both mesangial IgA and subepithelial IgG deposits were demonstrated by immunofluorescence and immunoelectron microscopy. Electron microscopic studies by immunogold method showed localization of IgA (diameter 15nm gold particles) within mesangial dense deposits and IgG (diameter 15nm gold particles) within subepithelial dense deposits. Overlapping IgA and membranous nephropathy was revealed in the same diabetic glomeruli with functional and biochemical alternations.

(PDF emailed within 1 workday: $29.90)

Accession: 039038868

Download citation: RISBibTeXText

PMID: 1484412

Related references

Partial remission by cyclosporine monotherapy in a patient with membranous nephropathy superimposed diabetic nephropathy. Cen Case Reports 5(2): 219-222, 2017

Renal outcome of IgA nephropathy superimposed on diabetic nephropathy in NIDDM patients. Journal of the American Society of Nephrology 9(PROGRAM AND ABSTR ISSUE): 118A, Sept, 1998

The Usefulness of Phospholipase A2 Receptor and IgG4 Detection in Differentiation Primary Membranous Nephropathy From Secondary Membranous Nephropathy in Renal Biopsy. Applied Immunohistochemistry and Molecular Morphology 26(8): 591-598, 2017

Ki-67 expression in glomeruli of IgA nephropathy, membranous nephropathy and diabetic nephropathy. Journal of Investigative Medicine 46(1): 153A, 1998

A case of anti-GBM glomerulonephritis superimposed on HBV-associated membranous nephropathy. Cen Case Reports 2(2): 239-247, 2013

Complement c 5b 9 complex is found in subepithelial deposits of stage i idiopathic membranous nephropathy but not of stage i de novo membranous nephropathy and toxic induced membranous nephropathy. Kidney International 26(4): 633, 1984

Goodpasture's Syndrome Superimposed on Membranous Nephropathy. A Case Report. The International Journal of Artificial Organs 18(12): 763-765, 1995

Goodpasture's syndrome superimposed on membranous nephropathy. A case report. International Journal of Artificial Organs 18(12): 763-765, 1995

Serum IgA levels in patients with diabetic nephropathy and IgA nephropathy superimposed on diabetes mellitus. Diabetes Research & Clinical Practice 48(2): 113-118, 2000

A case of anti-glomerular basement membrane glomerulonephritis superimposed on membranous nephropathy. Nephrology, Dialysis, Transplantation 15(8): 1238-1241, 2000

Prospective study on renal outcome of IgA nephropathy superimposed on diabetic glomerulosclerosis in type 2 diabetic patients. Nephrology, Dialysis, Transplantation 16(6): 1183-1188, 2001

Anti-glomerular basement membrane disease superimposed on membranous nephropathy: a case report and review of the literature. Journal of Medical Case Reports 4: 237, 2010

Circulating factors in sera or peripheral blood mononuclear cells in patients with membranous nephropathy or diabetic nephropathy. Journal of Korean Medical Science 12(6): 539-544, 1998

Can murine diabetic nephropathy be separated from superimposed acute renal failure?. Kidney International 68(1): 391-398, 2005

Localization of C3d in renal tissues of patients with membranous nephropathy and IgA nephropathy. Nihon Jinzo Gakkai Shi 29(9): 1161-1165, 1987