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A preliminary report on a study of serum alpha-1-antitrypsin and immunoglobulin levels in lepromatous leprosy

A preliminary report on a study of serum alpha-1-antitrypsin and immunoglobulin levels in lepromatous leprosy

Annals of the New York Academy of Sciences 278: 125-128

IgG, IgA, and IgM immunoglobulins and alpha-1-antitrypsin globulin in sera from 30 patients with lepromatous leprosy were determined and compared with 30 age- and sex-matched healthy controls. Mean levels of IgG, IgM, IgA, and alpha-1-antitrypsin were significantly elevated in the sera of lepromatous leprosy patients in comparison with levels found in normal subjects. Statistical analysis of the relationships between levels of alpha-1-antitrypsin and immunoglobulins in the sera of lepromatous leprosy patients and controls revealed no correlation. It is therefore concluded that factors responsible for concentrations of immunoglobulins and alpha-1-antitrypsin are independent of each other in patients with lepromatous leprosy.

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Accession: 039099718

Download citation: RISBibTeXText

PMID: 1085591

DOI: 10.1111/j.1749-6632.1976.tb47023.x

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