+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

A preliminary report on a study of serum alpha-1-antitrypsin and immunoglobulin levels in lepromatous leprosy



A preliminary report on a study of serum alpha-1-antitrypsin and immunoglobulin levels in lepromatous leprosy



Annals of the New York Academy of Sciences 278: 125-128



IgG, IgA, and IgM immunoglobulins and alpha-1-antitrypsin globulin in sera from 30 patients with lepromatous leprosy were determined and compared with 30 age- and sex-matched healthy controls. Mean levels of IgG, IgM, IgA, and alpha-1-antitrypsin were significantly elevated in the sera of lepromatous leprosy patients in comparison with levels found in normal subjects. Statistical analysis of the relationships between levels of alpha-1-antitrypsin and immunoglobulins in the sera of lepromatous leprosy patients and controls revealed no correlation. It is therefore concluded that factors responsible for concentrations of immunoglobulins and alpha-1-antitrypsin are independent of each other in patients with lepromatous leprosy.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 039099718

Download citation: RISBibTeXText

PMID: 1085591

DOI: 10.1111/j.1749-6632.1976.tb47023.x


Related references

Alpha-1-antitrypsin levels in lepromatous blood serum. International Journal of Leprosy and other Mycobacterial Diseases 39(2): 456-457, 1971

The HLA association of lepromatous leprosy and borderline lepromatous leprosy in Turkey. A preliminary study. International Journal of Dermatology 27(4): 246-247, 1988

Lack of effect of oral 4-phenylbutyrate on serum alpha-1-antitrypsin in patients with alpha-1-antitrypsin deficiency: a preliminary study. Journal of Pediatric Gastroenterology and Nutrition 39(1): 34-37, 2004

Alpha-1-antitrypsin deficiency in children: liver disease is not reflected by low serum levels of alpha-1-antitrypsin - a study on 48 pediatric patients. European Journal of Medical Research 10(12): 509-514, 2005

Lack of Effect of Oral 4-Phenylbutyrate on Serum Alpha-1-Antitrypsin in Patients with ??-1-Antitrypsin Deficiency: A Preliminary Study. Journal of Pediatric Gastroenterology & Nutrition 39(1): 34-37, 2004

Undernutrition and lepromatous leprosy. Serum vitamin A and E levels in leprosy spectrum. Indian Journal of Leprosy 60(1): 66-70, 1988

A study of estimation of serum alpha-1-antitrypsin in various forms of leprosy. Leprosy in India 53(3): 417-424, 1981

Serum immunoglobulin profile and C3 level in lepromatous leprosy patients. Leprosy in India 54(3): 454-460, 1982

Correlation of euglobulin immunoglobulin G levels with erythema nodosum leprosum in lepromatous leprosy. Clinical Immunology and Immunopathology 8(2): 335-344, 1977

Biochemical intermediates in alpha 1-antitrypsin deficiency: residual family resemblance for total alpha 1-antitrypsin, oxidized alpha 1-antitrypsin, and immunoglobulin E after adjustment for the effect of the Pi locus. Genetic Epidemiology 7(2): 137-149, 1990

Light and electron microscopic study of peripheral nerve damage in patients with lepromatous leprosy and borderline lepromatous leprosy. Hiroshima Journal of Medical Sciences 49(1): 83-92, 2000

The limitations of serum alpha-1 antitrypsin levels in patients with chronic liver disease and heterozygous alpha-1 antitrypsin deficiency. Gut 60(Suppl 1): A57-A58, 2011

Serum levels of alpha-1 antitrypsin predict phenotypic expression of the alpha-1 antitrypsin gene in the pediatric population. Gastroenterology 114(4 Part 2): A1345, 1998

Chronic bronchitis: concentration of alpha-1-antitrypsin (alpha-1-Pi), alpha-2-microglobulin (alpha-2-Pi), C-reactive protein, alpha-1 acid glycoprotein, immunoglobulin A (IgA) and secretory IgA in sputum and serum. Praxis und Klinik der Pneumologie 40(6): 266-273, 1986

Liver cirrhosis and abnormally low serum levels of alpha-1 antitrypsin in the absence of alpha-1 antitrypsin deficiency. Modern Pathology 9(1): 138A, 1996