+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Alkaline phosphatase isozymes in cultured human cancer cells



Alkaline phosphatase isozymes in cultured human cancer cells



Experientia 41(11): 1357-1361



Alkaline phosphatase, an ubiquitous enzyme is known to exist in several isozymic forms. At least three different isozymes have now been identified in humans. Alkaline phosphatase isozymes are among the substances synthesized ectopically by a variety of human tumors and many continuous cell lines derived from different cancers have retained the capacity to produce these membrane-located glycoproteins. This paper reviews the identification of alkaline phosphatase isozymes in cultured tumor cells and relates these findings with recent developments concerning these cell membrane located glycoproteins.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 039213784

Download citation: RISBibTeXText

PMID: 3905429

DOI: 10.1007/bf01949989


Related references

Studies on enz alkaline phosphatase isozymes enz alkaline leukocyte phosphatase isozymes rabbit human inst electrophoresis. Jikeikai Medical Journal: 123-124, 1968

Structural requirements for inhibition of alkaline phosphatase activity and for repression of alkaline phosphatase levels in cultured human cells by analogues of cysteine. Bull N Y Acad Med 41(2): 224, 1965

Tissue-non-specific alkaline phosphatase mRNA expression and alkaline phosphatase activity following application of retinoic acid in cultured human dental pulp cells. Archives of Oral Biology 44(10): 861-869, 1999

Nuclear localization of alkaline phosphatase in cultured human cancer cells. Medical Electron Microscopy 36(1): 47-51, 2003

Intracellular alkaline phosphatase activity in cultured human cancer cells. Histochemistry 73(1): 1-13, 1981

Presence of an unusual alkaline phosphatase in cultured human rectal cancer cells. Gastroenterology 82(5 Part 2): 1134, 1982

Hormone induction of alkaline phosphatase in cultured human cancer cells the effect of cell density. Journal of Cell Biology 107(6 Part 3): 404A, 1988

The role of receptors in hormone mediated regulation of alkaline phosphatase in cultured human cancer cells hela. Anatomical Record 199(3): 12A, 1981

Monoclonal antibodies block the bromelain-mediated release of human placental alkaline phosphatase from cultured cancer cells. Febs Letters 179(2): 316-320, 1985

Localization of alkaline phosphatase isozymes in human cancer cell lines in vitro. Acta Histochemica et Cytochemica 12(6): 631, 1979

Inhibition of growth and increase of alkaline phosphatase activity in cultured human oral cancer cells by all-trans retinoic acid. International Journal of Oral and Maxillofacial Surgery 35(7): 643-648, 2006

Ultra cytochemical localization of alkaline phosphatase isozymes in human cancer cell lines in vitro. Journal of Electron Microscopy 30(1): 100, 1981

Ultra cytochemical localization of alkaline phosphatase ec 3.1.3.1 isozymes in human cancer cell lines in vitro. Acta Histochemica et Cytochemica 14(3): 223-235, 1981

Enzymo histochemical studies on alkaline phosphatase isozymes in human and dog gastric carcinoma cells. Acta Histochemica et Cytochemica 14(1): 61, 1981