Assignment of a gene for human quinoid-dihydropteridine reductase (QDPR, EC 1.6.5.1) to chromosome 4

Kuhl, P.; Olek, K.; Wardenbach, P.; Grzeschik, K.H.

Human Genetics 53(1): 47-49

1979


ISSN/ISBN: 0340-6717
PMID: 295043
DOI: 10.1007/bf00289450
Accession: 039336035

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Abstract
An acrylamide gel electrophoretic procedure is described which allows the separation of human quinoid-dihydropteridine reductase (QDPR), EC 1.6.5.1) from the homologous enzyme expressed in established rodent cell lines. The human enzyme marker segregates exclusively with chromosome 4 in a series of well characterized man-mouse somatic cell hybrid clones from our clone bank. This observation supports the assignment of a structural gene for QDPR to human chromosome 4.

Assignment of a gene for human quinoid-dihydropteridine reductase (QDPR, EC 1.6.5.1) to chromosome 4