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Carcinogenic activity of ethylene oxide and its reaction products 2-chloroethanol, 2-bromoethanol, ethylene glycol and diethylene glycol. III. Research on ethylene glycol and diethylene glycol for carcinogenic effects

Dunkelberg, H.

Zentralblatt für Bakteriologie Mikrobiologie und Hygiene. Serie B Umwelthygiene Krankenhaushygiene Arbeitshygiene Praventive Medizin 183(4): 358-365

1987

ISSN/ISBN: 0932-6073
PMID: 3109147
Accession: 039455119
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Ethylene glycol and diethylene glycol were each administered once weekly subcutaneously to groups of 100 female NMRI mice at 3 dosages (30; 10 und 3 mg single dose per mouse). Tricaprylin was used as solvent. The mean total dosage per mouse was 2110.5; 707.0 and 196.2 mg for ethylene glycol and 2029.8; 671.7 and 213.3 mg for diethylene glycol. Neither ethylene glycol nor diethylene glycol induced tumors at the injection site or away from the point of administration.

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