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Change in the permeability of the blood-aqueous humor barrier in sulcus-fixed posterior capsule lenses

Change in the permeability of the blood-aqueous humor barrier in sulcus-fixed posterior capsule lenses

Fortschritte der Ophthalmologie 86(6): 550-553

In eyes in which posterior chamber lens implantation with sulcus fixation had been performed more than 2 years previously, the pathohistological findings showed that trophic changes can be caused in the area of the back surface of the iris and ciliary body. By means of fluorophotometric measurements, we studied the extent to which persistent disturbances in the blood-intraocular fluid barrier could be demonstrated postoperatively - even in eyes with no clinical evidence of impairment. Of the 33 eyes examined, 26 showed no ophthalmological findings, 2 eyes showed pronounced atrophy of the iris in the region of the adjacent lens tactile, and in 5 eyes piercing of the iris occurred through the lens haptic postoperatively. In all cases, the procedure had been performed at least 2 years ago. None of the patients noticed any impairment of vision. In the 26 eyes without ophthalmoscopically visible damage of the iris and ciliary body, there was no increase of fluorescein in the medium in the anterior chamber (mean value: -11 +/- 39). On the other hand, in the 5 eyes with perforation of the iris, there was a slight increase in the staining (mean value: +9.8 +/- 45), but it was not statistically significant.

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Accession: 039497395

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PMID: 2625278

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