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Characteristics of Crimean-Congo hemorrhagic fever virus (Xinjiang strain) in China

Characteristics of Crimean-Congo hemorrhagic fever virus (Xinjiang strain) in China

American Journal of Tropical Medicine and Hygiene 34(6): 1179-1182

Virus strains isolated from blood of patients during a hemorrhagic fever outbreak in 1968 in southern Xinjiang, China, from Hyalomma asiaticum and from sheep, were found to be identical or closely related to Crimean-Congo hemorrhagic fever (C-CHF) virus by complement fixation and indirect immunofluorescence tests with convalescent sera of patients and with C-CHF reference antibody. The virus was inactivated by ether and acid. Viral synthesis was not suppressed by 5-iododeoxyuridine suggesting an RNA-containing genome. The buoyant density in sucrose was 1.16-1.18 g/cm3. The particle weight was estimated at 3.26 +/- 0.46 X 10(8). The diameter of the virus particles was 85-105 nm.

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Accession: 039512641

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PMID: 2422968

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