+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn

+ Translate
+ Recently Requested

Circadian rhythm of REM sleep of chronic alcoholics during alcohol withdrawal

Circadian rhythm of REM sleep of chronic alcoholics during alcohol withdrawal

Drug and Alcohol Dependence 18(1): 77-85

Sleep structures were polygraphically investigated during the alcohol withdrawal periods of six male alcoholics. Polygraphic recordings were taken 10 days, 1 month and 3 months after hospitalization. Total sleep time was almost equal among the three recording nights for each patient. Stages 3 and 4 sleep were remarkably reduced on all the recording nights. REM sleep time was normal throughout the study. REM latency decreased in many patients on the 10th day, and gradually increased on the following nights. A very important change was observed in the distribution of REM sleep. Maximal duration was noted in the first REM episode on the 10th day in four of the six. On the second recording night the second REM episode was the longest in five of the six subjects. On the last recording night many patients exhibited a normal distribution of REM sleep. These findings which suggest that the acrophase of REM sleep is advanced by several hours for a few months after alcohol withdrawal have also been observed in patients with endogenous depression. Although our patients did not show any depressive symptoms during the study, one of them developed a severely depressive state after he began to drink alcohol thereafter.

(PDF emailed within 0-6 h: $19.90)

Accession: 039555106

Download citation: RISBibTeXText

PMID: 3780412

DOI: 10.1016/0376-8716(86)90116-X

Related references

Circadian rhythm of rapid eye movement sleep of chronic alcoholics during alcohol withdrawal. Drug & Alcohol Dependence 18(1): 77-86, 1986

The sleep pattern of chronic alcoholics during the alcohol withdrawal period. Folia Psychiatrica et Neurologica Japonica 34(2): 89-96, 1980

The body temperature rhythm during alcohol withdrawal and after withdrawal treatment in alcoholics. Neurosciences 20(SUPPL ): P69-P72, 1994

Circadian rhythm in hormone release during alcohol withdrawal and after withdrawal. Neurosciences 21(SUPPL ): P167-P170, 1995

Circadian sleep regulation in the absence of light perception: chronic non-24-hour circadian rhythm sleep disorder in a blind man with a regular 24-hour sleep-wake schedule. Sleep 16(4): 333-343, 1993

Sleep, psychological and clinical changes during alcohol withdrawal in NAD-treated alcoholics. Quarterly Journal of Studies on Alcohol 32(4): 982-994, 1971

Quantitative changes of signs and symptoms associated with acute alcohol withdrawal: incidence, severity and circadian effects in experimental studies of alcoholics. Advances in Experimental Medicine and Biology 59: 615-631, 1975

Melatonin and cortisol circadian secretion during ethanol withdrawal in chronic alcoholics. Chronobiologia 21(1-2): 109-112, 1994

Insulin effect in chronic alcoholics during alcohol withdrawal. Diabetologia 22(3): 215-216, 1982

An electrophysiological study on the alcohol withdrawal in chronic alcoholics. Seishin Shinkeigaku Zasshi 72(6): 596-617, 1970

Hypertension in early alcohol withdrawal in chronic alcoholics. Alcohol and Alcoholism 41(1): 5-10, 2005

Association of hyperhomocysteinemia to alcohol withdrawal in chronic alcoholics. Indian Journal of Clinical Biochemistry 23(2): 150-153, 2008

Measurements of change during alcohol withdrawal in chronic alcoholics. British Journal of Addiction to Alcohol and Other Drugs 65(4): 273-280, 1970

Types of sleep disorders in chronic alcoholics in the withdrawal period. Zhurnal Nevropatologii i Psikhiatrii Imeni S.S. Korsakova 72(6): 893-897, 1972

Clinical features of alcoholics after alcohol withdrawal--withdrawal syndrome, protracted withdrawal syndrome and prolonged disturbance of alcohol dependence. Nihon Rinsho. Japanese Journal of Clinical Medicine 55 Suppl: 393-405, 1997