+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Comparative activity in vitro of 16 antimicrobial agents against penicillin-susceptible meningococci and meningococci with diminished susceptibility to penicillin



Comparative activity in vitro of 16 antimicrobial agents against penicillin-susceptible meningococci and meningococci with diminished susceptibility to penicillin



Antimicrobial Agents and ChemoTherapy 33(9): 1622-1623



Broad-spectrum cephalosporins were very active against strains of Neisseria meningitidis with both penicillin susceptibility and diminished penicillin susceptibility. Ceftriaxone was the most active antibiotic. Increases in MIC for 90% of meningococci with diminished susceptibility to penicillin of greater than or equal to 16-fold were observed for amdinocillin, cefuroxime, aztreonam, and imipenem; 2-fold increases were observed for ceftazidime, mezlocillin, and piperacillin. No differences were observed for non-beta-lactam antibiotics.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 039614451

Download citation: RISBibTeXText

PMID: 2510596

DOI: 10.1128/aac.33.9.1622


Related references

Antimicrobial susceptibility of penicillin-sensitive and penicillin-resistant meningococci. Journal of Antimicrobial ChemoTherapy 35(5): 687-690, 1995

A comparative study of the in-vitro activity of cefepime and other antimicrobial agents against penicillin-susceptible and penicillin-resistant Streptococcus pneumoniae. Journal Of Antimicrobial Chemotherapy. 32(Suppl. B): 13-19, 1993

Comparative Susceptibility of Yersinia enterocolitica, Eikenella corrodens, and Penicillin-Resistant and Penicillin-Susceptible Streptococcus pneumoniae to -Lactam and Alternative Antimicrobial Agents. Clinical Infectious Diseases 4(Suppl. 2): S406-S410, 1982

Comparative susceptibility of Yersinia enterocolitica, Eikenella corrodens, and penicillin-resistant and penicillin-susceptible Streptococcus pneumoniae to beta-lactam and alternative antimicrobial agents. Reviews of Infectious Diseases 4 Suppl: S406-S410, 1982

E test for studying in vitro activity of seven antimicrobial agents against penicillin-susceptible and penicillin-resistant pneumococci. Chinese Medical Journal 113(7): 628-631, 2000

In vitro susceptibility of meningococci to antimicrobial agents. Antimicrobial Agents and ChemoTherapy 10: 531-533, 1970

Susceptibility of penicillin-resistant and penicillin-susceptible Streptococcus pneumoniae to newer antimicrobial agents. Journal of ChemoTherapy 11(3): 191-194, 1999

Meningococci with reduced susceptibility to penicillin. Lancet 335(8693): 863-864, 1990

Invasive meningococci with reduced susceptibility to penicillin in Portugal. Journal of Antimicrobial ChemoTherapy 49(2): 424-425, 2002

High frequency of reduced susceptibility to penicillin in serogroup 29E meningococci. Clinical Microbiology and Infection 6(4): 229-230, 2000

Sensitivity of meningococci to penicillin and sulfathiazole in vitro. Acta Path Et Microbiol Scand 23: 372-378, 1946

The interaction of penicillin and chloramphenicol against meningococci in vitro. Acta Pathologica et Microbiologica Scandinavica Section B Microbiology 87(2): 103-108, 1979

Penicillin resistance to meningococci in vitro and in vivo. Zeitschrift für Hygiene und Infektionskrankheiten; Medizinische Mikrobiologie Immunologie und Virologie 136(3): 293-310, 1953

In vitro activity of cefepime and cefotaxime compared with 5 other agents against 350 penicillin-susceptible and penicillin-resistant Streptococcus pneumoniae. Abstracts of the Interscience Conference on Antimicrobial Agents & Chemotherapy 38: 167, 1998

In vitro activity of cefepime and cefotaxime compared to six other agents against 350 penicillin-susceptible and penicillin-resistant Streptococcus pneumoniae. Journal of ChemoTherapy 12(1): 17-21, 2000