Comparative studies of bronchial secretions in children with chronic, nontuberculous lung diseases. 3. the detection of lysozyme, transferrin, alpha 1-antitrypsin, alpha 2-macroglobulin, haptoglobin and alpha 1-acid glycoprotein
Stelzner, A.; Groh, A.; Lehnert, U.
Allergie und Immunologie 34(2): 99-108
In 166 bronchial secretions from 63 children with chronic nontuberculous lung diseases lysozyme, transferrin, alpha 1-antitrypsin, alpha 2-macroglobulin, haptoglobin and alpha 1-acid glycoprotein were estimated. In patients with hard bronchoscopic or bronchographic alterations a reduction of lysozyme, alpha 1-antitrypsin and alpha 2-macroglobulin could be found. These proteins were measured more frequently in cases with dark altered mucosa. Moreover no relation could be found between transferrin, alpha 1-antitrypsin and alpha 2-macroglobulin and the outbreak of the diseases. -In bacterial contaminated secretions transferrin could be demonstrated more frequently in comparison with sterile bronchial secretions.