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Comparison of debrisoquine and guanethidine in treatment of hypertension



Comparison of debrisoquine and guanethidine in treatment of hypertension



British Medical Journal 1(5956): 482-485



A cross-over trail of debrisoquine and guanethidine in 32 patients showed that both drugs were equally effective in lowering both systolic and diastolic blood pressure. The degree to which they were tolerated by the patients, however, differed greatly. After three months on each drug 18 patients preferred debrisoquine, nine preferred guanethidine, and five showed no particular preference. At current prices the cost of daily treatment to the patient was cheaper with debrisoquine than with guanethidine.

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Accession: 039628562

Download citation: RISBibTeXText

PMID: 1125586

DOI: 10.1136/bmj.1.5956.482


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