+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Comparison of decalcified freeze-dried bone allograft and porous particulate hydroxyapatite in human periodontal osseous defects



Comparison of decalcified freeze-dried bone allograft and porous particulate hydroxyapatite in human periodontal osseous defects



Journal of Periodontology 60(12): 647-654



The purpose of this study was to clinically compare the healing potential of the osteoinductive decalcified freeze-dried bone allograft (DFDBA) with an osteoconductive synthetic graft, particulate porous hydroxyapatite (HA). Six patients ranging in age from 28 to 52 (mean age 42.6) participated in this investigation. They were without significant systemic disorders and had advanced periodontitis with at least two comparable periodontal defects. Each patient received initial therapy consisting of oral hygiene instruction, scaling, root planing, and occlusal adjustment as indicated. Probing pocket depth, gingival recession, attachment levels, and bleeding on probing were recorded in the posthygiene phase of therapy. Alveolar crest height and depth of osseous defect were obtained at the time of surgery. The cemento-enamel junction was used as the fixed reference point. All measurements were repeated at the time of a 6-month reentry. There was no significant difference in any of the soft tissue measurements when DFDBA and HA were compared. However, both treatment modalities reduced pocket depth and demonstrated a gain in clinical attachment levels. There was 2.2 mm of bone repair with DFDBA and 2.1 mm with HA. These values corresponded to a percent defect fill of 61% for DFDBA and 53% for HA. These values were likewise not statistically different.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 039628563

Download citation: RISBibTeXText

PMID: 2559181

DOI: 10.1902/jop.1989.60.12.647


Related references

A comparison of polylactic acid granules and decalcified freeze-dried bone allograft in human periodontal osseous defects. Journal of Periodontology 64(2): 103-109, 1993

Porous hydroxyapatite and decalcified freeze-dried bone in human periodontal defects. Journal of Periodontology 62(6): 407-407, 1991

Comparative clinical study of porous hydroxyapatite and decalcified freeze-dried bone in human periodontal defects. Journal of Periodontology 61(7): 399-404, 1990

A comparative evaluation of decalcified freeze dried bone allograft, hydroxyapatite and their combination in osseous defects of the jaws. Journal of Maxillofacial and Oral Surgery 9(3): 236-240, 2010

A comparison of freeze-dried bone allograft and demineralized freeze-dried bone allograft in human periodontal osseous defects. Journal of Periodontology 60(12): 655-663, 1989

A Clinical Comparison of Cenobone (A Decalcified Freeze-dried Bone Allograft) with Autogenous Bone Graft in the Treatment of Two- and Three-wall Intrabony Periodontal Defects: A Human Study with Six-month Reentry. Journal of Dental Research, Dental Clinics, Dental Prospects 2(1): 1-8, 2008

Comparison of freeze-dried bone allograft and porous hydroxylapatite in human periodontal defects. Journal of Periodontology 60(5): 231-237, 1989

Does a combination of platelet-rich plasma and decalcified freeze-dried bone allograft offer advantages over decalcified freeze-dried bone allograft alone when using pocket depth and clinical attachment level as markers for periodontal healing? A literature review. Journal of Investigative and Clinical Dentistry 2019: E12397-E12397, 2019

Decalcified freeze-dried bone allograft as an implant material in human periodontal defects. International Journal of Periodontics & Restorative Dentistry 4(6): 40-55, 1984

Comparative evaluation of decalcified freeze dried bone allograft with and without local doxycycline in non-contained human periodontal infrabony defects. Journal of Indian Society of Periodontology 17(4): 490-494, 2013

Antigenicity of freeze-dried cortical bone allograft in human periodontal osseous defects. Journal of Periodontology 59(6): 394-397, 1988

Combination treatment using decalcified freeze-dried bone allograft with guided tissue regeneration in human periodontal defects: two case reports. International Journal of Periodontics & Restorative Dentistry 14(4): 354-363, 1994

A six-month clinical evaluation of decalcified freeze-dried bone allografts in periodontal osseous defects. Journal of Periodontology 53(12): 726-730, 1982

Decalcified freeze-dried bone allograft combined with rich platelet derivatives for the treatment of human periodontal intrabony defects: a Meta-analysis. Hua Xi Kou Qiang Yi Xue Za Zhi 35(6): 636-642, 2018

Porous hydroxylapatite and decalcified freeze dried bone in periodontal defects after 18 months. Journal of Dental Research 69(SPEC ISSUE MAR): 380, 1990