+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Cytophotometric studies of the DNA, nucleic acid and protein content of liver cell nuclei from patients with virus hepatitis



Cytophotometric studies of the DNA, nucleic acid and protein content of liver cell nuclei from patients with virus hepatitis



Acta Pathologica et Microbiologica Scandinavica. Section A, Pathology 84(1): 1-8



Cytophotometric studies of the DNA, nucleic acid and protein content of liver cell nuclei from patients with virus hepatitis. Acta path. microbiol. scand. Sect. A, 84: 1-8, 1976. With a view to investigating some of the causes why the size of liver cell nuclei increase in virus hepatitis, the nuclear size and the nuclear contents of DNA, nucleic acid and protein were measured by cytophotometry. The liver cell nuclei could be grouped in classes according to their contents of DNA, nucleic acid, and protein and, as in control livers, diploid nuclei were always most frequent. Nuclei with intermediate DNA values, probably S-phase nuclei, were more frequent in hepatitis livers than in controls. The average size of nuclei from patients with hepatitis was significantly larger than that from controls, whereas the DNA content was the same. A significant, positive correlation between nucleic acid content, protein content and nuclear area was found. The high correlation between nuclear protein content and nuclear size simultaneously with the increased nuclear size during hepatitis is assumed to reflect an increased nuclear function.

(PDF emailed within 0-6 h: $19.90)

Accession: 039733569

Download citation: RISBibTeXText

PMID: 1251729

DOI: 10.1111/j.1699-0463.1976.tb00103.x


Related references

Cytophotometric studies of the DNA, nucleic acid and protein content of human liver cell nuclei. Acta Cytologica 20(2): 151-157, 1976

Biochemical and Cytophotometric Study of the Nucleic Acid and Protein Contents of Rat Liver Nuclei After Cortisone Injection. Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales 158: 1303-1307, 1964

Cytophotometric studies of the DNA content in mouse liver cell nuclei under conditions of C-avitaminosis. Tsitologiya 9(5): 602-606, 1967

Studies on hepatitis in hamsters infected with equine abortion virus. II. Changes in protein, nucleic acid, and weight of isolated hepatic nuclei. American Journal of Pathology 33(5): 1009-1022, 1957

Cytophotometric studies of the nucleic acid content in normal and in Coxsackie B3 virus infected cells of HEp-2 tissue culture. Tsitologiia 9(6): 707-712, 1967

Nucleic acid and protein composition of neopl hela cell nuclei isolated by 3 methods rat liver nuclei citric acid triton n 101. Experimental Cell Research: 46-52, 1969

Nucleic acid content in cell nuclei of the liver during development of the human foetus. Ukr Biokhim Zh 39(3): 292-296, 1967

Thyroxine effect on nucleic acid and protein content in liver nuclei of albino rats. Voprosy Meditsinskoi Khimii: 281-286, 1970

Cytophotometric studies of DNA content in liver nuclei of mice in vitamin C deficiency. Tsitologiia 9(5): 602-606, 1967

Serum protein and nucleic acid content in the liver of rabbits having toxic hepatitis and cirrhosis of the liver. Byulleten' Eksperimental'noi Biologii i Meditsiny 67(5): 36-39, 1969

Nucleic acid and histone content of liver cell nuclei and mitochondria in early human ontogenesis. Ukrains'kyi Biokhimichnyi Zhurnal 43(3): 375-380, 1971

Cytophotometric study of diurnal changes in the DNA content of liver cell nuclei from 11-12 day old chick embryos. Soobshcheniya Akademii Nauk Gruzinskoi SSR 77(1): 217-220, 1975

Variations of the content of desoxyribonucleic acid in interphasic nuclei as a function of cellular activity and their relationship with the variations of nuclear volume Nucleic acids: DNA in tumors and in virus infections: Cell activity and DNA content of interphasic nuclei. Handb Histochem 3(3): 54-115, 1966

The comparative nucleic acid content of liver nuclei, ova nuclei and spermatozoa of the frog. Experimental Cell Research 12(2): 249-253, 1957

Cytophotometric studies on desoxyribonucleic acid content in the polymorphous nuclei of the epididymis in mice. Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales 152(4): 652-655, 1958