Section 40
Chapter 39,855

Diuretic effect of a combined preparation of frusemide and slow-release potassium chloride

Davis, B.; Warrington, S.J.

Current Medical Research and Opinion 5(9): 739-742


ISSN/ISBN: 0300-7995
PMID: 738078
DOI: 10.1185/03007997809110215
Accession: 039854811

Download citation:  

An open randomized crossover study was carried out in 10 healthy volunteers to compare the diuretic effect of a single tablet combining 40 mg frusemide and a slow-release formulation of 600 mg potassium chloride with that of the two agents given in separate tablets. The results showed that both treatments had a similar effect on urinary volume and on sodium and potassium excretion, but the hourly urinary volumes during the first 6 hours suggested that the diuretic action of the combined formulation occurred slightly earlier after administration.

Full Text Article emailed within 0-6 h: $19.90