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Early and late B-cell development in the mouse



Early and late B-cell development in the mouse



Current Opinion in Immunology 4(2): 171-176



A common principle in B-cell development is the stringent selection of cells expressing appropriate antibody V regions as surface receptors. Cells failing to do so appear destined to rapid death. These life-death decisions are mediated by signals whose nature is not yet understood but whose generation involves immunoglobulin receptor complexes on B cells and B-cell progenitors.

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Accession: 039887663

Download citation: RISBibTeXText

PMID: 1605906

DOI: 10.1016/0952-7915(92)90008-3


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