+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Effect of levonorgestrel intrauterine device on human endometrial estrogen and progesterone receptors



Effect of levonorgestrel intrauterine device on human endometrial estrogen and progesterone receptors



Zhonghua Fu Chan Ke Za Zhi 26(5): 293-4, 323



Estrogen and progesterone cytoplasmic receptors (ER, PgR) were determined by radiochemical DCC technique in the endometria of 16 normal women at before child bearing age and 6 to 9 months after LNG IUD insertion. The study showed that both ER and PgR were reduced significantly after LNG IUD insertion (P less than 0.01). The decrease of ER and PgR might play an important role in gland reduction and endometrial atrophy. It may be one mechanism of the contraceptive effect and the cause of anemia or spotting between menstruation during the course of LNG IUD insertion.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 039928280

Download citation: RISBibTeXText

PMID: 1935411


Related references

The effect of a levonorgestrel-releasing intrauterine device on human endometrial oestrogen and progesterone receptors after one year of use. Human Reproduction 14(4): 970-975, 1999

Effects of levonorgestrel-releasing intrauterine system on endometrial estrogen and progesterone receptors in patients with endometrial hyperplasia. Nan Fang Yi Ke Da Xue Xue Bao 32(9): 1350-1354, 2013

Effect of levonorgestrel IUD and oral medroxyprogesterone acetate on glandular and stromal progesterone receptors (PRA and PRB), and estrogen receptors (ER-α and ER-β) in human endometrial hyperplasia. Yearbook of Obstetrics Gynecology and Women's Health 2007: 221-222, 2007

Effect of levonorgestrel IUD and oral medroxyprogesterone acetate on glandular and stromal progesterone receptors (PRA and PRB), and estrogen receptors (ER-alpha and ER-beta) in human endometrial hyperplasia. Gynecologic Oncology 101(2): 214-223, 2005

Endometrial estrogen and progestin receptors in women bearing a progesterone-releasing intrauterine device. Contraception 22(1): 19-23, 1980

Transdermal estrogen with a levonorgestrel-releasing intrauterine device for climacteric complaints versus estradiol-releasing vaginal ring with a vaginal progesterone suppository: Clinical and endometrial responses. Maturitas 26(2): 103-111, 1997

The effect of intrauterine levonorgestrel use on the expression of c-JUN, oestrogen receptors, progesterone receptors and Ki-67 in human endometrium. Molecular Human Reproduction 4(12): 1110-1115, 1999

The effect of intrauterine levonorgestrel use on the expression of c- Jun, oestrogen receptors, progesterone receptors and Ki-67 in human endometrium. Molecular Human Reproduction 4(12): 1110-1115, 1998

Transdermal estrogen with a levonorgestrel-releasing intrauterine device for climacteric complaints: Clinical and endometrial responses. American Journal of Obstetrics and Gynecology 172(1 PART 1): 114-119, 1995

Endometrial morphology during hormone replacement therapy with estradiol gel combined to levonorgestrel-releasing intrauterine device or natural progesterone. Acta Obstetricia Et Gynecologica Scandinavica. 77(7): 758-763,., 1998

Inhibition of DNA synthesis in isolated human endometrial cells by a levonorgestrel-releasing intrauterine device. Analytical and Quantitative Cytology and Histology 21(5): 409-412, 1999

Progression of atypical endometrial hyperplasia to adenocarcinoma despite intrauterine progesterone treatment with the levonorgestrel-releasing intrauterine system. Obstetrics and Gynecology 111(2 Pt 2): 547-549, 2008

Endometrial estrogen and progesterone receptors in women wearing intrauterine contraceptive devices. Zhonghua Fu Chan Ke Za Zhi 20(3): 160-3, 190, 1985

The effect of levonorgestrel-releasing intrauterine device (20 micrograms/day) (LNG-IUD-20) on the morphological structure of human endometrium: a study of the endometrial factor VIII activity in the women before and after insertion of LNG-IUD-20 by the digital image analysis. Contraception 52(1): 63-68, 1995

Hysteroscopic Endometrial Focal Resection followed by Levonorgestrel Intrauterine Device Insertion as a Fertility-Sparing Treatment of Atypical Endometrial Hyperplasia and Early Endometrial Cancer: A Retrospective Study. Journal of Minimally Invasive Gynecology 2018, 2018