+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Effect of posture on the single-breath oxygen test in normal subjects



Effect of posture on the single-breath oxygen test in normal subjects



Journal of Applied Physiology 41(4): 474-479



The effect of posture on phase III (alveolar nitrogen plateau) and phase IV (closing capacity) of the single-breath oxygen test was examined in 10 normal people. In part 1 of the study, subjects inspired and expired in the standing, supine, prone, and right lateral decubitus positions; there was no effect of posture on phase IV but slopes of phase III were higher when subjects were in the supine and lateral positions. In part 2, subjects inspired in the standing position and expired in one of the recumbent positions. Phase IV occurred infrequently except in the prone position (6 of 10 subj); slopes of phase III in part 2 were not consistently altered by changing posture. It is difficult to explain the failure of posture to alter phase IV solely on a model requiring a linear gradient of pleural pressure. The slope of phase III appears to depend more on the emptying patterns of small regions with widely varying volume-to-ventilation ratios than on gravity-dependent sequences of emptying. Finally, the data suggest a considerable similarity between the upright and prone positions in terms of lung filling and emptying.

(PDF emailed within 0-6 h: $19.90)

Accession: 039936323

Download citation: RISBibTeXText

PMID: 985389

DOI: 10.1152/jappl.1976.41.4.474


Related references

Age and smoking dependency of the single breath oxygen test in healthy normal subjects. Bulletin de Physio-Pathologie Respiratoire 8(1): 174, 1972

Effect of cold pressor test on single-breath DLCO in normal subjects. Journal of Applied Physiology 76(2): 750-755, 1994

Effect of fasting subjects' posture on 13C-urea breath test for detection of Helicobacter pylori infection. Helicobacter 2(2): 82-85, 1997

Age and smoking dependency of the single-breath oxygen test in healthy subjects. Pneumonologie. Pneumonology 147(1): 46-51, 1972

Rapid pre emptying decreases the slope of phase iii of the single breath nitrogen test in normal subjects. Federation Proceedings 41(5): ABSTRACT 8630, 1982

Intrapulmonary gas distribution. A comparison of the helium mixing time and nitrogen single breath test in normal and diseased subjects. American Review of Respiratory Disease 102(5): 750-759, 1970

The effect of dose and osmolality of lactulose on the oral cecal transit time determined by the hydrogen breath test and the reproducibility of the test in normal subjects. Annals of Clinical Research 17(6): 331-333, 1985

The aminopyrine breath test day to day variation and effect of activity in normal subjects. Gastroenterology 90(5 PART 2): 1731, 1986

Standards and significance for three tests of the distribution of ventilation. The time to equilibration, the forced equilibrating expiration and the Fowler single breath test: normal subjects. American Journal of Medicine 48(4): 424-433, 1970

Effect of meal size and test duration on gastric emptying as determined by breath test in normal subjects using a muffin meal labeled with 13C-sodium octanoate. Gastroenterology 118(4 Suppl 2 Part 1): AGA A143, 2000

Comparison of lung volume measurements by single breath helium and multiple breath nitrogen equilibration methods in normal subjects and COPD patients. Respiration; International Review of Thoracic Diseases 49(1): 52-60, 1986

Effect of decreasing expired flow on the rate of carbon mon oxide uptake within a single breath in normal subjects. American Review of Respiratory Disease 113(4): 256, 1976

Components of the single breath carbon monoxide transfer factor responses to exercise and posture in young adult subjects. Journal of Physiology (Cambridge) 432: 40P, 1991

Effect of nitro glycerin on single breath diffusing capacity for carbon mon oxide of normal subjects at rest and during exercise. Journal of Applied Physiology Respiratory Environmental & Exercise Physiology 52(4): 851-856, 1982

Comparison of lung volume measurements by single breath helium and multiple breath nitrogen equilibration methods in normal subjects and chronic obstructive pulmonary disease patients. Respiration 49(1): 52-60, 1986