+ Site Statistics
References:
52,654,530
Abstracts:
29,560,856
PMIDs:
28,072,755
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn

+ Translate
+ Recently Requested

Effect of sea nettle (Chrysaora quinquecirrha) venom on isolated rat aorta



Effect of sea nettle (Chrysaora quinquecirrha) venom on isolated rat aorta



Toxicon 26(12): 1209-1212



The venom from sea nettle (Chrysaora quinquecirrha) (1-10 micrograms/ml) produced an irreversible contraction of the isolated rat aortic ring that was slow in onset, increased with time, and reached maximum in about 10-20 min. The contraction was not inhibited by pretreatment with phenoxybenzamine, atropine, indomethacin, tetrodotoxin, ouabain, low Na+ or Na+-free medium, however, it was markedly decreased by the Ca2+ channel blockers, nifedipine and verapamil. In Ca2+-free medium, no increase in tension was produced by the venom. It is concluded that sea nettle venom causes a contraction of the rat aortic ring by increasing Ca2+ influx through the voltage-dependent Ca2+ channels.

(PDF emailed within 0-6 h: $19.90)

Accession: 039939742

Download citation: RISBibTeXText

PMID: 2907190

DOI: 10.1016/0041-0101(88)90306-6


Related references

Sea nettle (Chrysaora quinquecirrha) nematocyst venom hemagglutinins. Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology 74(1): 225-228, 1983

Characterization of chrysaora quinquecirrha sea nettle nematocyst venom collagenase. Comparative Biochemistry & Physiology B 69(3): 529-534, 1981

Human immunosuppression induced by sea nettle (Chrysaora quinquecirrha) venom. Toxicon 29(3): 386-390, 1991

Sea nettle (Chrysaora quinquecirrha) nematocyst venom: mechanism of action on muscle. Toxicon 21(1): 81-95, 1983

Immunosorbent chromatography of sea nettle (Chrysaora quinquecirrha) venom and characterization of toxins. Toxicon 21(3): 385-391, 1983

Toxicity of sea nettle (Chrysaora quinquecirrha) fishing tentacle nematocyst venom in cultured rat hepatocytes. Toxicon 34(7): 771-778, 1996

Partial purification and characterization of the acid protease of sea nettle (Chrysaora quinquecirrha) nematocyst venom. Comparative Biochemistry and Physiology. B, Comparative Biochemistry 72(1): 93-97, 1982

Partial purification and characterization of the alkaline protease of sea nettle chrysaora quinquecirrha nematocyst venom. Comparative Biochemistry & Physiology C Comparative Pharmacology 74(2): 361-364, 1983

Production of a mono clonal antibody against the sea nettle chrysaora quinquecirrha venom mouse lethal factor. Proceedings of the Society for Experimental Biology & Medicine 167(3): 374-377, 1981

Enzyme linked immuno sorbent assay to detect anti sea nettle chrysaora quinquecirrha venom antibodies. Experientia (Basel) 37(9): 1005-1007, 1981

Antitumor and antioxidant role of Chrysaora quinquecirrha (sea nettle) nematocyst venom peptide against Ehrlich ascites carcinoma in Swiss Albino mice. Molecular and Cellular Biochemistry 338(1-2): 69-76, 2010

The effect of light on strobilation in the chesapeake bay sea nettle chrysaora quinquecirrha. Marine Biology (Berlin) 20(2): 144-147, 1973

Effect of Chrysaora quinquecirrha (sea nettle) toxin on rat nerve and muscle. Toxicon 8(2): 179-181, 1970