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Ethambutol and the optic nerve



Ethambutol and the optic nerve



Bulletin des Societes d'Ophtalmologie de France 89(8-9): 1001-1003



Author describe two clinical observations of optic neuropathy due to the systemic absorption of antibiotics used against tuberculosis. Two items are pointed out: swelling of the optic disc and functional improvement of electro-physiologic and colorimetric tests 6 months after the end of the treatment. He think that optic disc swelling is the clinical manifestation of an anatomical and volumetrical increase of the neuronal axon due to blockade of the axoplasmic transport without demyelinating lesions. This could explain the functional improvement.

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Accession: 040054305

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PMID: 2620414


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