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Evaluation of two immunofluorescence assays with monoclonal antibodies for typing of herpes simplex virus



Evaluation of two immunofluorescence assays with monoclonal antibodies for typing of herpes simplex virus



Journal of Clinical Microbiology 21(4): 643-644



An indirect immunofluorescence assay and a direct immunofluorescence assay were evaluated for typing clinical isolates of herpes simplex virus (HSV). The indirect immunofluorescence assay (Electro-Nucleonics, Inc.) correctly identified 16 HSV type 2 (HSV-2) isolates, but failed to identify 4 of 14 HSV-1 isolates because of background fluorescence and instability of reagents. Forty-nine HSV-1 isolates were correctly typed by direct immunofluorescence assay (Kallestad Laboratories, Inc.), but 1 of 39 HSV-2 isolates did not react with the HSV-2 type-specific antibody conjugate.

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Accession: 040074869

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PMID: 2985651



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