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Gentamicin kinetics in the blood and aqueous humor of the rabbit eye after intramuscular and subconjunctival administration

Sieradzki, E.; Strauss, K.; Olejarz, E.; Pankowska, I.; Pankowski, M.; Kałuzny, J.

Klinika Oczna 93(2-3): 45-46

1991


ISSN/ISBN: 0023-2157
PMID: 1870290
Accession: 040211043

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Investigations were performed in rabbits which were given gentamycin intramuscularly and subconjunctivally. After subconjunctival application gentamycin passes quickly into the eye and its therapeutical level persists up to 1 hour. After intramuscular injection gentamycin is passing slower into the aqueous but persists there longer (the therapeutical level--up to 5.5 hours).

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