+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Guide for the Salmonella typhimurium/mammalian microsome tests for bacterial mutagenicity



Guide for the Salmonella typhimurium/mammalian microsome tests for bacterial mutagenicity



Mutation Research 189(2): 83-91



Since its development by Dr. Bruce Ames and his coworkers, the Salmonella typhimurium/mammalian microsome mutagenicity assay has been used widely throughout the world. Many authors have suggested various modifications and made recommendations in regards to this assay. Although the recommendations of a panel of experts was published in 1979 by de Serres and Shelby, a committee of members of the Environmental Mutagen Society (EMS) initiated this effort in response to the encouragement by the American Society of Testing and Materials (Committee E47.09.01) and because of new developments within the field of microbial mutagenesis testing. Its purpose is to provide a guide for people who perform or evaluate microbial mutagenesis tests, but it is not intended for these recommendations to replace or diminish the usefulness of presently available protocols and procedures.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 040234509

Download citation: RISBibTeXText

PMID: 3309640

DOI: 10.1016/0165-1218(87)90014-0


Related references

Mutagenicity tests with gallic acid and tannic acid in the salmonella typhimurium mammalian microsome assay. Journal of Environmental Science & Health Part B Pesticides Food Contaminants & Agricultural Wastes 20(2): 153-166, 1985

Mutagenicity of pyrrolizidine alkaloids in the Salmonella typhimurium/mammalian microsome system. Mutation Research 281(2): 143-147, 1992

Mutagenicity of cosmetic dyes using the salmonella typhimurium mammalian microsome test. Abstracts of the Annual Meeting of the American Society for Microbiology 78 : 204, 1978

Lack of mutagenicity of some phyto estrogens in the salmonella typhimurium mammalian microsome assay. Mutation Research 78(4): 317-322, 1980

Comparative mutagenicity of halogenated pyridines in the Salmonella typhimurium/mammalian microsome test. Mutation Research 176(2): 185-198, 1987

Salmonella typhimurium mammalian microsome mutagenicity testing for detecting carcinogens and mutagens. Benesova, O , Z Rychter And R Jelinek (Ed ) Evaluation Of Embryotoxicity, Mutagenicity And Carcinogenicity Risks in New Drugs; Proceedings Of The 3rd Symposium on Toxiciological Testing For Safety Of New Drugs, Prague, Czechoslovakia, Apr 6-8, L976 324p Univerzita Karlova: Prague, Czechoslovakia Illus : p271-276, 1979

Mutagenicity of n nitroso pyridinol carbamate with the salmonella typhimurium mammalian microsome test. Cancer Letters 7(2-3): 135-140, 1979

The activity of s 9 liver fractions from 7 species in the salmonella typhimurium mammalian microsome mutagenicity test. Mutation Research 70(3): 279-300, 1980

Mutagenicity testing of some drug and cosmetic dye lakes with the salmonella typhimurium mammalian microsome assay. Mutation Research 66(2): 181-186, 1979

Mutagenicity of disperse dyes in ames salmonella typhimurium and mammalian microsome reverse mutation assay. Environmental & Molecular Mutagenesis Supplement (20): 8, 1992

Mutagenicity of compounds identified in pulp and paper mill effluents using the salmonella typhimurium mammalian microsome assay. Geneticspart 2 Suppl: S66, 1979

Polar organic compounds in urban aerosols identification and mutagenicity in the salmonella typhimurium mammalian microsome bioassay. Zentralblatt fuer Bakteriologie Mikrobiologie und Hygiene Abt 1 Originale B Hygiene Umwelthygiene Krankenhaushygiene Arbeitshygiene Praeventive Medizin 181(1-2): 28-29, 1985

Studies on the influence of microbiological factors and activation on the results of the salmonella typhimurium mammalian microsome mutagenicity test. Mutation Research 85(6): 437-438, 1981

Concentration of neutral polar organic compounds in urban aerosols and their mutagenicity with the salmonella typhimurium mammalian microsome bioassay. Zentralblatt fuer Bakteriologie Mikrobiologie und Hygiene Abt 1 Originale B Hygiene Umwelthygiene Krankenhaushygiene Arbeitshygiene Praeventive Medizin 181(3-5): 453, 1985

Mutagenicity tests with gallic and tannic acid in the Salmonella/mammalian microsome assay. Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes 20(2): 153-165, 1985