HPLC-determination of apomorphine in a mormyrid fish, gnathonemus petersii

Noe, A.; Kunze, P.

Zeitschrift für Naturforschung. C Journal of Biosciences 44(11-12): 917-919

1989


ISSN/ISBN: 0939-5075
PMID: 2631732
DOI: 10.1515/znc-1989-11-1207
Accession: 040242118

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Abstract
Uptake of apomorphine and elimination kinetics in brain and muscle tissue of the weakly electric fish Gnathonemus petersii (Mormyridae) was determined by HPLC. 20 min exposure of the fish to apomorphine in the aquarium water (0.4 mg/l) resulted in a concentration factor of 1.09 for brain and 0.55 for muscle tissue. Elimination from brain tissue can be described with first order kinetics (t1/2 = 2.4 h).