+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Hemodynamic effects of "expresso" Italian coffee and pure caffeine on healthy volunteers

Hemodynamic effects of "expresso" Italian coffee and pure caffeine on healthy volunteers

Cardiologia 35(7): 575-580

In 15 healthy non-coffee-drinker subjects and in 5 usual coffee-drinkers, the effects were studied of 2 cups of "espresso" italian coffee and of 200 mg purified caffeine on blood pressure, heart rate, forearm rest flow and peripheral resistance. In the 15 non-coffee-drinkers, left ventricular ejection fraction, fractional shortening, cardiac output and end-systolic stress were also evaluated by a 2D-guided M-mode echocardiogram before and 60 and 120 min after oral administration of 200 mg purified caffeine. In the non-coffee-drinker volunteers, diastolic and systolic blood pressure and peripheral resistance increased both after "espresso" coffee and after caffeine. In the usual drinkers no hemodynamic effect was seen. No variation of cardiac contractility was observed. We conclude that caffeine contained in the "espresso" coffee obtained with the high-pressure italian procedure is a strong vasoconstrictor agent, while it has no action on cardiac contractility.

(PDF emailed within 1 workday: $29.90)

Accession: 040264101

Download citation: RISBibTeXText

PMID: 2088602

Related references

Comparison of the cardio vascular effects of caffeine following oral coffee ingestion and intra venous caffeine administration in healthy volunteers. Clinical Research: 632a, 1982

Hemodynamic effects of coffee and caffeine in normal volunteers a placebo controlled clinical study. Journal of Internal Medicine 229(6): 501-504, 1991

Evaluation of electrocardiographic and hemodynamic effects of caffeine with acute dosing in healthy volunteers. PharmacoTherapy 21(4): 437-442, 2001

Subjective effects of modafinil, a new central adrenergic stimulant in healthy volunteers: A comparison with amphetamine, caffeine, caffeine and placebo. European Psychiatry 8(4): 201-208, 1993

Antioxidant effects after coffee enema or oral coffee consumption in healthy Thai male volunteers. Human & Experimental Toxicology 31(7): 643-651, 2012

Caffeine in sport. Urinary excretion of caffeine in healthy volunteers after intake of common caffeine-containing beverages. South African Medical Journal 74(4): 163-164, 1988

Effects of nondetected caffeine in healthy volunteers. Therapie 39(3): 325, 327-325, 327, 1984

Haemodynamic effects of coffee and purified caffeine in normal volunteers: a placebo-controlled clinical study. Journal of Human Hypertension 6(2): 95-99, 1992

The effects on respiratory metabolism produced by equal amounts of caffeine in the form of coffee, tea and the pure alkaloid. Jour Nutrition 27(4): 287-293, 1944

Stimulation of arithmetic skills and hemodynamic effects by coffee-drinking: double-blind analysis with different concentrations of caffeine. Journal of Nara Medical Association 45(3): 290-300, 1994

Hemodynamic effects of labetalol in healthy volunteers. International Journal of Clinical Pharmacology, Therapy, and Toxicology 20(11): 517-519, 1982

Caffeine and eeg mapping effects of a visuo spatial task in healthy volunteers. Neurophysiologie Clinique 18(4): 355-368, 1988

The effect of lorazepam and caffeine , alone and in combination, on the electroencephalogram of healthy, caffeine withdrawn volunteers. British Journal of Clinical Pharmacology 37(5): 502P, 1994

Hemodynamic and electrocardiographic effects of almotriptan in healthy volunteers. Journal of Cardiovascular Pharmacology 37(3): 280-289, 2001

Hemodynamic effects of reboxetine in healthy male volunteers. Clinical Pharmacology and Therapeutics 66(3): 282-287, 1999