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Hemofiltration clearance of flecainide in a patient with acute renal failure



Hemofiltration clearance of flecainide in a patient with acute renal failure



Intensive Care Medicine 14(3): 236-237



Flecainide, a new antiarrhythmic drug, has been shown not no be removed to a significant extent by hemodialysis or peritoneal dialysis, in spite of a high renal clearance. Its systemic and hemofiltrate clearances, measured in a patient under continuous hemofiltration, were 402 and 19.7 ml/min respectively. The clearance ratio of less than 5% makes the contribution of hemofiltration to the elimination of flecainide clinically negligible.

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Accession: 040265000

Download citation: RISBibTeXText

PMID: 3132493

DOI: 10.1007/bf00717997


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