+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Immune responses in mice infected with lactic dehydrogenase virus. I. Antibody response to DNP-BGG and hyperglobulinaemia in BALB/c mice



Immune responses in mice infected with lactic dehydrogenase virus. I. Antibody response to DNP-BGG and hyperglobulinaemia in BALB/c mice



Immunology 32(6): 981-988



The humoral immune response to DNP-BGG of BALB/c mice acutely infected with lactic dehydrogenase virus (LDV) has been investigated. Virus-infected mice injected with antigen in saline exhibit a greater anti-DNP response than uninfected controls. When this antigen is presented in Freund's complete adjuvant (FCA) the anti-DNP response is greater than obtained with antigen in saline, but significant differences between infected and uninfected controls are not observed. These data are consistent with the view that acute LDV infection can have an adjuvant-like effect when this T-dependent antigen is introduced in saline. In addition, the effect of viral infection on plasma Ig class and subclass levels has been investigated. LDV infection leads to a gradual increase in plasma Ig concentration. This effect is restricted to the IgG2a subclass in most animals, but occasionally is restricted to IgG1. The mechanisms responsible for these changes have not been delineated.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 040354629

Download citation: RISBibTeXText

PMID: 885591


Related references

Immune responses in mice infected with lactic dehydrogenase virus. III. Antibody response to a T-dependent and a T-independent antigen during acute and chronic LDV infection. Cellular Immunology 50(2): 253-260, 1980

Immune response to lactate dehydrogenase (LDH) isoenzymes in normal mice and in mice infected with lactic dehydrogenase virus (LDV). Journal of Medical Microbiology 6(2): Px-Xi, 1973

Immune response to lactate dehydrogenase iso enzymes in normal mice and in mice infected with lactic dehydrogenase virus. Journal of Medical Microbiology 6(2): X-XI, 1973

Reduction of plasma clearance rates and immune response by negative charges lactic dehydrogenase iso enzymes in normal and lactic dehydrogenase virus infected mice. RES Journal of the Reticuloendothelial Society 24(3): 227-242, 1978

Isolation of Clq-binding virus-antibody immune complexes from lactic dehydrogenase virus (LDV)-infected mice. Immunology 45(2): 365-370, 1982

Antibody classes and subclasses in circulating immune complexes isolated from mice infected with lactic dehydrogenase virus. Immunology 48(3): 511-517, 1983

Immune responses in mice infected with lactic dehydrogenase virus. IV. Functional status of the macrophage during acute LDV infection. Immunology 36(2): 241-246, 1979

Early changes in the kidneys of BALB-c mice infected with lactic dehydrogenase virus. Nature 248(5450): 686-687, 1974

Immune responses in mice infected with lactic dehydrogenase virus. II. Contact sensitization to DNFB and characterization of lymphoid cells during acute LDV infection. Cellular Immunology 29(2): 285-294, 1977

Studies on the clearance of lactic dehydrogenase iso enzymes from plasma of normal mice and mice infected with lactic dehydrogenase virus. Journal of Medical Microbiology 6(2):, 1973

Generation of antibody diversity in the immune response of balb c mice to influenza virus hem agglutinin 1. significant variation in repertoire expression between individual mice. Journal of Experimental Medicine 157(2): 687-704, 1983

Generation of antibody diversity in the immune response of Balb/c mice to influenza virus hemagglutinin. I. Significant variation in repertoire expression between individual mice. Journal of Experimental Medicine 157(2): 687-704, 1983

Delayed increase in plasma lactic dehydrogenase activity in mouse hepatitis virus-infected mice subsequently infected with lactic dehydrogenase virus. Laboratory Animal Science 37(6): 792-794, 1987

Deposition of immune complexes in the kidneys of mice infected with lactic dehydrogenase virus. Journal of Immunology 106(5): 1264-1266, 1971

Inhibition of cellular immune reactions in mice infected with lactic dehydrogenase virus. Nature 221(5183): 873-874, 1969